Perspective: A multicenter, randomized, double-blind, active-controlled study to evaluate the effects of LCZ696 compared to valsartan on cognitive function in patients with chronic heart failure and preserved ejection fraction Jan 1, 2017 - Dec 31, 2019
A clinical trial of LCZ verses valsartan in heart failure patients with preserved ejection fraction. The study uses MRI and PET scans to identify amyloid deposits in the brain and any adverse effects of cognitive function of teh study drug, LCZ696.
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IRONMAN: Effectiveness of Intravenous iron treatment vs standard care in patients with heart failure and iron deficiency: a randomised, open-label multicentre trial May 5, 2017 - Apr 30, 2022
A BHF funded study to compare the effect of additional intravenous iron IV therapy versus standard therapy for patients with chronic heart failure and left ventricular systolic dysfunction and iron deficiency.
Recruitment is 12 patients per ye...
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Galactic-HF: A Double-blind, Randomized, Placebo-controlled, Multicenter Study to Assess the Efficacy and Safety of Omecamtiv Mecarbil on Mortality and Morbidity in Subjects With Chronic Heart Failure With Reduced Ejection Fraction Apr 1, 2017 - Jul 31, 2021
Acronym is derived from : Global approach to lowering adverse cardiac outcomes through improving contractility in heart failure.
A phase III randomised placebo controlled clinical trial sponsored by Amgen Inc of omecamtiv mercabil, a study dru...
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SilHF: Sildenafil in Heart Failure Mar 3, 2014 - Jun 22, 2018
Respond CRT-D Jan 10, 2013 - Feb 8, 2017
BreatheMOR: Morphine for the relief of breathlessness in stable chronic heart failure Oct 1, 2013 - Feb 28, 2019
Opioids have been used for centuries to relieve pain and other symptoms. A meta-analysis in 2002 of eight randomised controlled trials (RCTs) showed that opioids had a clinically relevant beneficial effect on dyspnoea in people with mainly chronic ob...
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Cardiogoniometry Studies Apr 1, 2016 - Dec 31, 2017
α-synuclein is a key novel regulator of platelet function. Jan 1, 2020 - Dec 31, 2022
Non-Clinical PhD Studentship
SOLOIST: A Randomized, Double-Blind, Placebo-controlled, Parallel-group, Multicentre Study to Evaluate the Effects of SOtagliLiflozin on Clinical Outcomes in HemOdynamIcally STable Patients with Type 2 Diabetes POST worsening Heart Failure. Aug 1, 2018 - Jan 31, 2021
A Randomized, Double-Blind, Placebo-controlled, Parallel-group, Multicentre Study to Evaluate the Effects of SOtagliLiflozin on Clinical Outcomes in HemOdynamIcally STable Patients with Type 2 Diabetes POST worsening Heart Failure.
AZD9977: A Phase I, Open Label, Randomized, Parallel group, Multicentre study to Compare the Effect of AZD9977 and Spironolactone on Serum Potassium [sK+] during 28 days in Patients with HFmrEF or HFpEF and eGFR in the range of ≥40 and ≤70 mL/min/1.73m2 Feb 1, 2019 - Jan 31, 2020
A Phase I, Open Label, Randomized, Parallel group, Multicentre study to Compare the Effect of AZD9977 and Spironolactone on Serum Potassium [sK+] during 28 days in Patients with HFmrEF or HFpEF
and eGFR in the range of ≥40 and ≤70 mL/min/1.73m...
Comparing Outcomes of Through knee and Above knee Amputation Apr 17, 2019 - Dec 31, 2021