All Projects (69)

Soy and testosterone: T01057 - Double placebo controlled parallel trial of soy phytoestrogens in patients with compensated hypogonadism Oct 1, 2009 - Apr 30, 2019

TSB Costs (Study 1, 2, 3 & 4): In vitro and in vivo assessment of polyphenol extracts on cardiovascular indices Jan 1, 2012 - Aug 1, 2016
Evidence suggests dietary plant polyphenols are associated with reducing indices of cardiovascular disease such as endothelial dysfunction, insulin resistance and hypertension. The key objectives of this translational research proposal are to study a... Read More about TSB Costs (Study 1, 2, 3 & 4): In vitro and in vivo assessment of polyphenol extracts on cardiovascular indices.

Sandoz Ltd unfettered donation May 1, 2013 - Dec 31, 2017

Sir Jules Thorn PhD Scholarship Programme 2016 Sep 1, 2016 - Aug 31, 2019
Idiopathic pulmonary fibrosis (IPF) is a progressive scarring disease of the lungs that affects about 15,000 people in the UK. There is no curative treatment and 5-year survival in IPF is worse than many cancers. Despite this, the pathogenesis of IPF... Read More about Sir Jules Thorn PhD Scholarship Programme 2016.

Characterisation of monocyte CD200R in pulmonary sarcoidosis Mar 1, 2016 - Feb 28, 2018

Albiglutide + Insulin Glargine Versus Insulin Lispro + Insulin Glargine in the Treatment of Subjects with Type 2 Diabetes Mellitus: The switch Study Jun 1, 2015 - Aug 1, 2018

AFFERENT14: A Study to Assess the Effect of AF-219 on Cough Reflex Sensitivity in Both Healthy and Chronic Cough Subjects Oct 5, 2015 - Jul 31, 2018

DUAL 8: A 104 week clinical trial comparing long term glycaemic control of insulin degludec/liraglutide (IDegLira) versus insulin glargine therapy in subjects with type 2 diabetes mellitus Dec 1, 2015 - Feb 28, 2019

AFFERENT12: AF219-012: A 12 week Study to assess the Efficacy and tolerability of AF 219 in subjects with treatm Mar 1, 2016 - May 31, 2018

A double-blind, randomized control trial to evaluate the effect of high protein high fibre yogurts on weight loss in overweight and obese women Jun 1, 2015 - Dec 31, 2017

Service Users perspectives to accessing Type 2 Diabetes Services within East Riding of Yorkshire Jan 1, 2016 - Mar 31, 2019
adaptation of pfact 7856, which was a successful bid to Hull CCG. This is the same project for East Riding of Yorkshire CCG. Peer review for previous project attached.

Differentiating the malignant potential of pancreatic cysts Oct 1, 2017 - Dec 31, 2022
The effective diagnosis of pancreatic cancer is often quite challenging, due to a lack of disease-specific symptoms, resulting in the majority of patients presenting with advanced disease, with an associated dismal prognosis. Earlier detection of pan... Read More about Differentiating the malignant potential of pancreatic cysts.

Proof of Concept study (POC) to investigate the effect of ambroxol hydrochloride (20mg lozenges) on the cough reflex in patients with acute upper respiratory tract infection Oct 1, 2017 - Sep 30, 2018

TUSSIX: MTI-110 - A randomized, double-blind, placebo-controlled study of the efficacy, safety, and tolerability of Serlopitant for the treatment of refractory chronic cough Dec 1, 2017 - Nov 30, 2018

HHIPP: Hull Hip fracture Intervention and Prevention Programme Nov 1, 2019 - Dec 31, 2021

Transition in Type 1 Diabetes: Service Users’ Perspectives on the Transition from Children to Adult Type 1 Diabetes Mellitus Services within Hull and East Riding of Yorkshire Jun 1, 2018 - May 31, 2020

Development and pilot of the “Living with Polycystic Ovary Syndrome (PCOS)” structured education programme Apr 1, 2019 - Sep 30, 2021
Polycystic ovary syndrome (PCOS) is the most common endocrine condition in reproductive age group females and it is associated with various clinical features including irregular periods, male-pattern hair loss from the head and excess hair in other b... Read More about Development and pilot of the “Living with Polycystic Ovary Syndrome (PCOS)” structured education programme.

Two-part, double-blind, placebo-controlled, randomized, parallel-group study - (Part 1) in healthy male volunteers to assess safety and tolerability of ascending repeated oral doses of BAY 1817080 followed (Part 2), two-way crossover administration with four-step dose titration in patients with refractory chronic cough to assess safety, tolerability and efficacy for proof of concept and dose-finding Jul 18, 2018 - Dec 31, 2019

A single arm, open-label exploratory clinical trial of azithromycin in pulmonary sarcoidosis Mar 1, 2019 - Sep 30, 2020
Patients with sarcoidosis need treatment options that improve their disease without causing unacceptable side effects. Currently, steroids tablets are offered for severe sarcoidosis, but side effects can be dangerous and personally distressing, and s... Read More about A single arm, open-label exploratory clinical trial of azithromycin in pulmonary sarcoidosis.

BICS: A randomised, double-blind placebo controlled trial of the effectiveness of the beta-blocker bisoprolol in preventing exacerbations of chronic obstructive pulmonary disease Jun 1, 2017 - May 31, 2022