The biomechanical function of periodontal ligament fibres in orthodontic tooth movement (2014)
Journal Article
McCormack, S. W., Witzel, U., Watson, P. J., Fagan, M. J., & Gröning, F. (2014). The biomechanical function of periodontal ligament fibres in orthodontic tooth movement. PLoS ONE, 9(7), e102387. https://doi.org/10.1371/journal.pone.0102387

Orthodontic tooth movement occurs as a result of resorption and formation of the alveolar bone due to an applied load, but the stimulus responsible for triggering orthodontic tooth movement remains the subject of debate. It has been suggested that th... Read More about The biomechanical function of periodontal ligament fibres in orthodontic tooth movement.

In vivo cranial bone strain and bite force in the agamid lizard Uromastyx geyri (2014)
Journal Article
Porro, L. B., Ross, C. F., Iriarte-Diaz, J., O'Reilly, J. C., Evans, S. E., & Fagan, M. J. (2014). In vivo cranial bone strain and bite force in the agamid lizard Uromastyx geyri. The journal of experimental biology, 217(11), 1983-1992. https://doi.org/10.1242/jeb.096362

In vivo bone strain data are the most direct evidence of deformation and strain regimes in the vertebrate cranium during feeding and can provide important insights into skull morphology. Strain data have been collected during feeding across a wide ra... Read More about In vivo cranial bone strain and bite force in the agamid lizard Uromastyx geyri.

Mathematical modelling of the pathogenesis of multiple myeloma-induced bone disease (2014)
Journal Article
Ji, B., Genever, P. G., Patton, R. J., & Fagan, M. J. (2014). Mathematical modelling of the pathogenesis of multiple myeloma-induced bone disease. International journal for numerical methods in biomedical engineering, 30(11), 1085-1102. https://doi.org/10.1002/cnm.2645

Multiple myeloma (MM) is the second most common haematological malignancy and results in destructive bone lesions. The interaction between MM cells and the bone microenvironment plays an important role in the development of the tumour cells and MM-in... Read More about Mathematical modelling of the pathogenesis of multiple myeloma-induced bone disease.

Effects of cervical muscle fatigue on the perception of the subjective vertical and horizontal (2014)
Journal Article
Gosselin, G., & Fagan, M. J. (2014). Effects of cervical muscle fatigue on the perception of the subjective vertical and horizontal. SpringerPlus, 3(1), Article 78. https://doi.org/10.1186/2193-1801-3-78

Introduction: Cervical functional capacity outcome measures that are simple and reliable are urgently needed in order permit accurate assessment/reassessment during treatments and rehabilitation. Induced neck muscle fatigue has been shown to alter fu... Read More about Effects of cervical muscle fatigue on the perception of the subjective vertical and horizontal.

Development and three-dimensional morphology of the zygomaticotemporal suture in primate skulls (2014)
Journal Article
Curtis, N., Witzel, U., & Fagan, M. J. (2014). Development and three-dimensional morphology of the zygomaticotemporal suture in primate skulls. Folia primatologica, 85(2), 77-87. https://doi.org/10.1159/000357526

Cranial sutures are an essential part of the growing skull, allowing bones to increase in size during growth, with their morphology widely believed to be dictated by the forces and displacements that they experience. The zygomaticotemporal suture in... Read More about Development and three-dimensional morphology of the zygomaticotemporal suture in primate skulls.

A predator-prey based mathematical model of the bone remodelling cycle: Exploring the relationship between the model parameters and biochemical factors (2014)
Journal Article
Ji, B., Yang, Q., Genever, P. G., Patton, R. J., & Fagan, M. J. (2014). A predator-prey based mathematical model of the bone remodelling cycle: Exploring the relationship between the model parameters and biochemical factors. Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, 228(10), 1035-1042. https://doi.org/10.1177/0954411914554633

© IMechE 2014. Bone remodelling is a vital process which enables bone to repair, renew and optimize itself. Disorders in the bone remodelling process are inevitably manifested in bone-related diseases, such as hypothyroidism, primary hyperparathyroid... Read More about A predator-prey based mathematical model of the bone remodelling cycle: Exploring the relationship between the model parameters and biochemical factors.

The effects of cervical muscle fatigue on balance - A study with elite amateur rugby league players (2014)
Journal Article
Gosselin, G., & Fagan, M. J. (2014). The effects of cervical muscle fatigue on balance - A study with elite amateur rugby league players. Journal of sports science & medicine, 13(2), 329-337

Neck muscle fatigue has been shown to alter an individual’s balance in a similar way to that reported in subjects suffering from neck pain or subjects that have suffered a neck injury. The main purpose of the present study was to quantify the effects... Read More about The effects of cervical muscle fatigue on balance - A study with elite amateur rugby league players.

Erratum: Cranial sutures work collectively to distribute strain throughout the reptile skull (Journal of The Royal Society Interface (2013) 10 (2013044) DOI: 10.1098/rsif.2013.0442) (2013)
Journal Article
Curtis, N., Jones, M. E., Evans, S. E., O'Higgins, P., & Fagan, M. J. (2013). Erratum: Cranial sutures work collectively to distribute strain throughout the reptile skull (Journal of The Royal Society Interface (2013) 10 (2013044) DOI: 10.1098/rsif.2013.0442). Journal of the Royal Society interface / the Royal Society, 10(87), Article 2013044. https://doi.org/10.1098/rsif.2013.0584

Figure 4 was presented incorrectly, with (a) and (b) displaying the same bite position. The corrected figure below shows different bite positions for (a) and (b) as was initially intended.

The importance of accurate muscle modelling for biomechanical analyses: A case study with a lizard skull (2013)
Journal Article
Gröning, F., Jones, M. E., Curtis, N., Herrel, A., O'Higgins, P., Evans, S. E., & Fagan, M. J. (2013). The importance of accurate muscle modelling for biomechanical analyses: A case study with a lizard skull. Journal of the Royal Society interface / the Royal Society, 10(84), Article 20130216. https://doi.org/10.1098/rsif.2013.0216

Computer-based simulation techniques such as multi-body dynamics analysis are becoming increasingly popular in the field of skull mechanics. Multi-body models can be used for studying the relationships between skull architecture, muscle morphology an... Read More about The importance of accurate muscle modelling for biomechanical analyses: A case study with a lizard skull.

Cranial sutures work collectively to distribute strain throughout the reptile skull (2013)
Journal Article
Curtis, N., Fagan, M. J., Evans, S. E., Jones, M. E. H., & O'Higgins, P. (2013). Cranial sutures work collectively to distribute strain throughout the reptile skull. Journal of the Royal Society interface / the Royal Society, 10(86), 1-9. https://doi.org/10.1098/rsif.2013.0442

The skull is composed of many bones that come together at sutures. These sutures are important sites of growth, and as growth ceases some become fused while others remain patent. Their mechanical behaviour and how they interact with changing form and... Read More about Cranial sutures work collectively to distribute strain throughout the reptile skull.

The Head and Neck Anatomy of Sea Turtles (Cryptodira: Chelonioidea) and Skull Shape in Testudines (2012)
Journal Article
Jones, M. E., Werneburg, I., Curtis, N., Penrose, R., O'Higgins, P., Fagan, M. J., & Evans, S. E. (2012). The Head and Neck Anatomy of Sea Turtles (Cryptodira: Chelonioidea) and Skull Shape in Testudines. PLoS ONE, 7(11), Article e47852. https://doi.org/10.1371/journal.pone.0047852

Background: Sea turtles (Chelonoidea) are a charismatic group of marine reptiles that occupy a range of important ecological roles. However, the diversity and evolution of their feeding anatomy remain incompletely known. Methodology/Principal Finding... Read More about The Head and Neck Anatomy of Sea Turtles (Cryptodira: Chelonioidea) and Skull Shape in Testudines.

The effect of osteocyte apoptosis on signalling in the osteocyte and bone lining cell network: A computer simulation (2012)
Journal Article
Jahani, M., Genever, P. G., Patton, R. J., Ahwal, F., & Fagan, M. J. (2012). The effect of osteocyte apoptosis on signalling in the osteocyte and bone lining cell network: A computer simulation. Journal of biomechanics, 45(16), 2876-2883. https://doi.org/10.1016/j.jbiomech.2012.08.005

Osteocytes play a critical role in the regulation of bone remodelling by translating strain due to mechanical loading into biochemical signals transmitted through the interconnecting lacuno-canalicular network to bone lining cells (BLCs) on the bone... Read More about The effect of osteocyte apoptosis on signalling in the osteocyte and bone lining cell network: A computer simulation.

Comparing the distribution of strains with the distribution of bone tissue in a human mandible: a finite element study (2012)
Journal Article
Gröning, F., Fagan, M., & O'Higgins, P. (2013). Comparing the distribution of strains with the distribution of bone tissue in a human mandible: a finite element study. Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology, 296(1), 9-18. https://doi.org/10.1002/ar.22597

Comparative anatomy and experimental studies suggest that the mass and distribution of tissue within a bone is adapted to the strains the bone experiences during function. Finite element analysis is a powerful tool that can be used to investigate thi... Read More about Comparing the distribution of strains with the distribution of bone tissue in a human mandible: a finite element study.

Masticatory loadings and cranial deformation in Macaca fascicularis: a finite element analysis sensitivity study (2012)
Journal Article
Fitton, L. C., Shi, J. F., Fagan, M. J., & O'Higgins, P. (2012). Masticatory loadings and cranial deformation in Macaca fascicularis: a finite element analysis sensitivity study. Journal of anatomy, 221(1), 55-68. https://doi.org/10.1111/j.1469-7580.2012.01516.x

Biomechanical analyses are commonly conducted to investigate how craniofacial form relates to function, particularly in relation to dietary adaptations. However, in the absence of corresponding muscle activation patterns, incomplete muscle data recor... Read More about Masticatory loadings and cranial deformation in Macaca fascicularis: a finite element analysis sensitivity study.

Developing a musculoskeletal model of the primate skull: Predicting muscle activations, bite force, and joint reaction forces using multibody dynamics analysis and advanced optimisation methods (2012)
Journal Article
Shi, J., Curtis, N., Fitton, L. C., O'Higgins, P., & Fagan, M. J. (2012). Developing a musculoskeletal model of the primate skull: Predicting muscle activations, bite force, and joint reaction forces using multibody dynamics analysis and advanced optimisation methods. Journal of Theoretical Biology, 310, 21-30. https://doi.org/10.1016/j.jtbi.2012.06.006

An accurate, dynamic, functional model of the skull that can be used to predict muscle forces, bite forces, and joint reaction forces would have many uses across a broad range of disciplines. One major issue however with musculoskeletal analyses is t... Read More about Developing a musculoskeletal model of the primate skull: Predicting muscle activations, bite force, and joint reaction forces using multibody dynamics analysis and advanced optimisation methods.

Shearing Mechanics and the Influence of a Flexible Symphysis During Oral Food Processing in Sphenodon (Lepidosauria: Rhynchocephalia) (2012)
Journal Article
Jones, M. E. H., Evans, S. E., Curtis, N., O'Higgins, P., & Fagan, M. J. (2012). Shearing Mechanics and the Influence of a Flexible Symphysis During Oral Food Processing in Sphenodon (Lepidosauria: Rhynchocephalia). Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology, 295(7), 1075-1091. https://doi.org/10.1002/ar.22487

Functional evolution of the feeding system in rodents (2012)
Journal Article
Cox, P. G., Rayfield, E. J., Fagan, M. J., Herrel, A., Pataky, T. C., & Jeffery, N. (2012). Functional evolution of the feeding system in rodents. PLoS ONE, 7(4), e36299. https://doi.org/10.1371/journal.pone.0036299

The masticatory musculature of rodents has evolved to enable both gnawing at the incisors and chewing at the molars. In particular, the masseter muscle is highly specialised, having extended anteriorly to originate from the rostrum. All living rodent... Read More about Functional evolution of the feeding system in rodents.

Virtual functional morphology: novel approaches to the study of craniofacial form and function (2012)
Journal Article
O'Higgins, P., Fitton, L. C., Phillips, R., Shi, J., Liu, J., Gröning, F., …Fagan, M. (2012). Virtual functional morphology: novel approaches to the study of craniofacial form and function. Evolutionary Biology, 39(4), 521-535. https://doi.org/10.1007/s11692-012-9173-8

Modeling the human mandible under masticatory loads: which input variables are important? (2012)
Journal Article
Gröning, F., Fagan, M., & O'higgins, P. (2012). Modeling the human mandible under masticatory loads: which input variables are important?. Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology, 295(5), 853-863. https://doi.org/10.1002/ar.22455

Finite element analyses (FEA) that have simulated masticatory loadings of the human mandible differ significantly with regard to their basic input variables such as material properties, constraints, and applied forces. With sensitivity analyses it is... Read More about Modeling the human mandible under masticatory loads: which input variables are important?.

Improving the validation of finite element models with quantitative full-field strain comparisons (2012)
Journal Article
Gröning, F., Bright, J. A., Fagan, M. J., & O'Higgins, P. (2012). Improving the validation of finite element models with quantitative full-field strain comparisons. Journal of biomechanics, 45(8), 1498-1506. https://doi.org/10.1016/j.jbiomech.2012.02.009

The techniques used to validate finite element (FE) models against experimental results have changed little during the last decades, even though the traditional approach of using single point measurements from strain gauges has major limitations: the... Read More about Improving the validation of finite element models with quantitative full-field strain comparisons.