Improved DNA extraction efficiency from low level cell numbers using a silica monolith based micro fluidic device (2012)
Journal Article
Kashkary, L., Kemp, C., Shaw, K. J., Greenway, G. M., & Haswell, S. J. (2012). Improved DNA extraction efficiency from low level cell numbers using a silica monolith based micro fluidic device. Analytica Chimica Acta, 750, 127-131. https://doi.org/10.1016/j.aca.2012.05.019

The evaluation of a micro fluidic system with an integrated silica monolith for performing DNA extraction from limited biological samples has been carried out. Low DNA target concentrations usually require the addition of carrier RNA to ensure desire... Read More about Improved DNA extraction efficiency from low level cell numbers using a silica monolith based micro fluidic device.

Direct processing of clinically relevant large volume samples for the detection of sexually transmitted infectious agents from urine on a microfluidic device (2012)
Journal Article
Kemp, C., Birch, C., Shaw, K. J., Nixon, G. J., Docker, P. T., Greenman, J., …Dyer, C. E. (2012). Direct processing of clinically relevant large volume samples for the detection of sexually transmitted infectious agents from urine on a microfluidic device. Analytical Methods, 4(7), 2141-2144. https://doi.org/10.1039/c2ay25075f

Urine is a preferred specimen for nucleic acid-based detection of sexually transmitted infections (STIs) but represents a challenge for microfluidic devices due to low analyte concentrations. We present an extraction methodology enabling rapid on-chi... Read More about Direct processing of clinically relevant large volume samples for the detection of sexually transmitted infectious agents from urine on a microfluidic device.

Integrated DNA extraction and amplification using electrokinetic pumping in a microfluidic device (2011)
Journal Article
Parton, J., Birch, C., Kemp, C., Haswell, S. J., Pamme, N., & Shaw, K. J. (2012). Integrated DNA extraction and amplification using electrokinetic pumping in a microfluidic device. Analytical Methods, 4(1), 96-100. https://doi.org/10.1039/c1ay05552f

An integrated system employing anion exchange for the extraction of DNA from biological samples prior to polymerase chain reaction DNA amplification has been developed, based on microfluidic methodology utilising electrokinetic pumping. In this syste... Read More about Integrated DNA extraction and amplification using electrokinetic pumping in a microfluidic device.