Skip to main content

Research Repository

Advanced Search

Detection of doxycycline hyclate and oxymetazoline hydrochloride in pharmaceutical preparations via spectrophotometry and microfluidic paper-based analytical device (μPADs) (2020)
Journal Article
Abdulsattar, J. O., Hadi, H., Richardson, S., Iles, A., & Pamme, N. (2020). Detection of doxycycline hyclate and oxymetazoline hydrochloride in pharmaceutical preparations via spectrophotometry and microfluidic paper-based analytical device (╬╝PADs). Analytica Chimica Acta, 1136, 196-204. https://doi.org/10.1016/j.aca.2020.09.045

There is growing demand for simple to operate, sensitive, on-site quantitative assays to investigate concentrations of drug molecules in pharmaceutical preparations for quality assurance. Here, we report on the development of two colorimetric analysi... Read More about Detection of doxycycline hyclate and oxymetazoline hydrochloride in pharmaceutical preparations via spectrophotometry and microfluidic paper-based analytical device (μPADs).

Visualization of diffusion limited antimicrobial peptide attack on supported lipid membranes (2018)
Journal Article
Heath, G. R., Harrison, P. L., Strong, P. N., Evans, S. D., & Miller, K. (2018). Visualization of diffusion limited antimicrobial peptide attack on supported lipid membranes. Soft matter, 14(29), 6146-6154. https://doi.org/10.1039/c8sm00707a

Understanding the mechanism of action of antimicrobial peptides (AMP) is fundamental to the development and design of peptide based antimicrobials. Utilizing fast-scan atomic force microscopy (AFM) we detail the attack of an AMP on both prototypical... Read More about Visualization of diffusion limited antimicrobial peptide attack on supported lipid membranes.

Phospholipid dependent mechanism of smp24, an α-helical antimicrobial peptide from scorpion venom (2016)
Journal Article
Harrison, P. L., Heath, G. R., Johnson, B. R., Abdel-Rahman, M. A., Strong, P. N., Evans, S. D., & Miller, K. (2016). Phospholipid dependent mechanism of smp24, an ╬▒-helical antimicrobial peptide from scorpion venom. BBA - Biomembranes, 1858(11), 2737-2744. https://doi.org/10.1016/j.bbamem.2016.07.018

Determining the mechanism of action of antimicrobial peptides (AMPs) is critical if they are to be developed into the clinical setting. In recent years high resolution techniques such as atomic force microscopy (AFM) have increasingly been utilised t... Read More about Phospholipid dependent mechanism of smp24, an α-helical antimicrobial peptide from scorpion venom.