Dynamic risk stratification using Markov chain modelling in patients with chronic heart failure (2022)
Journal Article
Kazmi, S., Kambhampati, C., Cleland, J., Cuthbert, J., Kazmi, K. S., Pellicori, P., …Clark, A. L. (2022). Dynamic risk stratification using Markov chain modelling in patients with chronic heart failure. ESC Heart Failure, https://doi.org/10.1002/ehf2.14028

Aims: Risk changes with the progression of disease and the impact of treatment. We developed a dynamic risk stratification Markov chain model using artificial intelligence in patients with chronic heart failure (CHF). Methods and results: We describe... Read More about Dynamic risk stratification using Markov chain modelling in patients with chronic heart failure.

Integrated single-cell RNA sequencing analysis reveals alterations of ageing human lung endothelium heterogeneity in idiopathic pulmonary fibrosis (2022)
Working Paper
Faulkner, E. C., Moverley, A. A., Hart, S. P., & Nikitenko, L. L. Integrated single-cell RNA sequencing analysis reveals alterations of ageing human lung endothelium heterogeneity in idiopathic pulmonary fibrosis

Increasing age is the main risk factor for chronic lung diseases (CLD) including idiopathic pulmonary fibrosis (IPF). Halting or reversing progression of IPF remains an unmet clinical need due to limited knowledge of underlying mechanisms. In particu... Read More about Integrated single-cell RNA sequencing analysis reveals alterations of ageing human lung endothelium heterogeneity in idiopathic pulmonary fibrosis.

Predictors of diabetes-related distress before and after FreeStyle Libre-1 use: Lessons from the Association of British Clinical Diabetologists nationwide study (2021)
Journal Article
Deshmukh, H., Wilmot, E. G., Gregory, R., Barnes, D., Narendran, P., Saunders, S., …Sathyapalan, T. (2021). Predictors of diabetes-related distress before and after FreeStyle Libre-1 use: Lessons from the Association of British Clinical Diabetologists nationwide study. Diabetes, Obesity and Metabolism, 23(10), 2261-2268. https://doi.org/10.1111/dom.14467

Aim: To identify the baseline demographic and clinical characteristics associated with diabetes-related distress (DRD) and factors associated with improvement in DRD after initiating use of the FreeStyle Libre (FSL) in people living with type 1 diabe... Read More about Predictors of diabetes-related distress before and after FreeStyle Libre-1 use: Lessons from the Association of British Clinical Diabetologists nationwide study.

Tunable photon statistics exploiting the Fano effect in a waveguide (2019)
Journal Article
Foster, A. P., Hallett, D., Iorsh, I. V., Sheldon, S. J., Godsland, M. R., Royall, B., …Wilson, L. R. (2019). Tunable photon statistics exploiting the Fano effect in a waveguide. Physical review letters, 122(17), Article 173603. https://doi.org/10.1103/PhysRevLett.122.173603

A strong optical nonlinearity arises when coherent light is scattered by a semiconductor quantum dot coupled to a nanophotonic waveguide. We exploit the Fano effect in such a waveguide to control the phase of the quantum interference underpinning the... Read More about Tunable photon statistics exploiting the Fano effect in a waveguide.

Duramycin-porphyrin conjugates for targeting of tumour cells using photodynamic therapy (2016)
Journal Article
Broughton, L. J., Giuntini, F., Savoie, H., Bryden, F., Boyle, R. W., Maraveyas, A., & Madden, L. A. (2016). Duramycin-porphyrin conjugates for targeting of tumour cells using photodynamic therapy. Journal of photochemistry and photobiology. B, Biology, 163, 374-384. https://doi.org/10.1016/j.jphotobiol.2016.09.001

Duramycin, through binding with phosphatidylethanolamine (PE), has been shown to be a selective molecular probe for the targeting and imaging of cancer cells. Photodynamic therapy aims to bring about specific cytotoxic damage to tumours through deliv... Read More about Duramycin-porphyrin conjugates for targeting of tumour cells using photodynamic therapy.

Hull early walking aid for rehabilitation of trans-tibial amputees-randomised controlled trial (HEART) (2010)
Journal Article
Hancock, A., Mazari, F., Chetter, I., & Vanicek, N. (2010). Hull early walking aid for rehabilitation of trans-tibial amputees-randomised controlled trial (HEART). British journal of surgery, 97, 67 - 68

TRPA1 is activated by direct addition of cysteine residues to the N-hydroxysuccinyl esters of acrylic and cinnamic acids (2010)
Journal Article
Sadofsky, L. R., Boa, A. N., Maher, S. A., Birrell, M. A., Belvisi, M. G., & Morice, A. H. (2011). TRPA1 is activated by direct addition of cysteine residues to the N-hydroxysuccinyl esters of acrylic and cinnamic acids. Pharmacological research : the official journal of the Italian Pharmacological Society, 63(1), 30-36. https://doi.org/10.1016/j.phrs.2010.11.004

The nociceptor TRPA1 is thought to be activated through covalent modification of specific cysteine residues on the N terminal of the channel. The precise mechanism of covalent modification with unsaturated carbonyl-containing compounds is unclear, th... Read More about TRPA1 is activated by direct addition of cysteine residues to the N-hydroxysuccinyl esters of acrylic and cinnamic acids.

Plasma tissue factor, a predictor for restenosis following percutaneous transluminal angioplasty (2005)
Journal Article
Ray, B., Ettles, D., Lee, D., Robinson, G., Bryce, J., Mylankal, K., …Ettelaie, C. (2005). Plasma tissue factor, a predictor for restenosis following percutaneous transluminal angioplasty. British journal of surgery, 92(4), 502 - 502. https://doi.org/10.1002/bjs.5038

Temporary balloon catheter occlusion for control of haemorrhage following penetrating axillary artery injury (2004)
Journal Article
Mehta, T., Venkata Subramaniam, A., Chetter, I., Nicholson, A., & Wilkinson, A. (2004). Temporary balloon catheter occlusion for control of haemorrhage following penetrating axillary artery injury. European Journal of Vascular and Endovascular Surgery Extra, 8(2), 29-30. https://doi.org/10.1016/j.ejvsextra.2004.05.014

Penetrating injuries of the axillary artery are uncommon. Their repair can be difficult in the presence of torrential haemorrhage, which obscures the surgical field. We describe the use of interventional radiology for temporary control of bleeding to... Read More about Temporary balloon catheter occlusion for control of haemorrhage following penetrating axillary artery injury.

The value of abdominal examination in the diagnosis of abdominal aortic aneurysm (2004)
Journal Article
Venkatasubramaniam, A., Mehta, T., Chetter, I., Bryce, J., Renwick, P., Johnson, B., …McCollum, P. (2004). The value of abdominal examination in the diagnosis of abdominal aortic aneurysm. European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 27(1), 56-60. https://doi.org/10.1016/j.ejvs.2003.09.006

Background. There is considerable variability in the reported value of clinical examination in the diagnosis of abdominal aortic aneurysms (AAA). This study aims to assess accuracy of abdominal examination by a doctor, a nurse and the patient in the... Read More about The value of abdominal examination in the diagnosis of abdominal aortic aneurysm.

POSSUM-based models accurately predict mortality for aortic aneurysm repair (2002)
Journal Article
Kuhan, G., Abidia, A., Chetter, I., Johnson, B., Wilkinson, A., Renwick, P., & McCollum, P. (2002). POSSUM-based models accurately predict mortality for aortic aneurysm repair. British journal of surgery, 89(4), 517 - 518. https://doi.org/10.1046/j.0007-1323.2001.02021.x

Appropriate use of carotid duplex imaging: results of a prospective audit (2002)
Journal Article
Nicholson, A., Wilkinson, A., Johnson, B., Kuhan, G., Bryce, J., McCollum, P., …Chetter, I. (2002). Appropriate use of carotid duplex imaging: results of a prospective audit. British journal of surgery, 89(5), 657 - 657. https://doi.org/10.1046/j.1365-2168.2002.02096.x

POSSUM and P-POSSUM overpredict mortality for carotid endarterectomy (2002)
Journal Article
Kuhan, G., Abidia, A. F., Wijesinghe, L. D., Chetter, I. C., Johnson, B. F., Wilkinson, A. .., …McCollum, P. T. (2002). POSSUM and P-POSSUM overpredict mortality for carotid endarterectomy. European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 23(3), 209-211. https://doi.org/10.1053/ejvs.2001.1557

Objectives: the aim was to test the predictive accuracy of POSSUM and P-POSSUM on patients undergoing CEA. Design: retrospective and prospective study. Materials: 499 CEAs performed by four vascular surgeons from a single unit from 1992-99. The media... Read More about POSSUM and P-POSSUM overpredict mortality for carotid endarterectomy.

Detecting abdominal aortic aneurysms – assessing the value of clinical examination (2002)
Journal Article
Venkatasubramaniam, A. K., Chetter, I., Mehta, T., Kuhan, G., Abidia, A., Bryce, J., …McCollum, P. (2002). Detecting abdominal aortic aneurysms – assessing the value of clinical examination. Irish journal of medical science, 171(S1), 25-26. https://doi.org/10.1007/bf03170371

Risk modelling study for carotid endarterectomy (2001)
Journal Article
Kuhan, G., Gardiner, E. D., Abidia, A. F., Chetter, I. C., Renwick, P. M., Johnson, B. F., …McCollum, P. T. (2001). Risk modelling study for carotid endarterectomy. British journal of surgery, 88(12), 1590-1594. https://doi.org/10.1046/j.0007-1323.2001.01938.x

Background: The aims of this study were to identify factors that influence the risk of stroke or death following carotid endarterectomy (CEA) and to develop a model to aid in comparative audit of vascular surgeons and units. Methods: A series of 839... Read More about Risk modelling study for carotid endarterectomy.

A logistic regression model for Carotid endareterectomy (2001)
Journal Article
Kuhan, G., Chetter, I., Abidia, A., Renwick, P., Johnson, B., Wilkinson, A., & McCollum, P. (2001). A logistic regression model for Carotid endareterectomy. Cardiovascular Surgery -Oxford-, 9(S2), 30-33. https://doi.org/10.1016/s0967-2109%2801%2900068-0

Logistic regression model for carotid endarterectomy (2001)
Journal Article
Abidia, A., Wilkinson, A., Johnson, B., Gardiner, E., Kuhan, G., McCollum, P., …Chetter, I. (2001). Logistic regression model for carotid endarterectomy. British journal of surgery, 88(5), 735 - 735. https://doi.org/10.1046/j.1365-2168.2001.01741.x

POSSUM and P-POSSUM in the comparative audit of patients undergoing carotid endarterectomy (2001)
Journal Article
Abidia, A., Wilkinson, A., Johnson, B., Kuhan, G., McCollum, P., Renwick, P., & Chetter, I. (2001). POSSUM and P-POSSUM in the comparative audit of patients undergoing carotid endarterectomy. British journal of surgery, 88(5), 766 - 766

Risk modelling for carotid endarterectomy (2001)
Journal Article
Abidia, A., Wilkinson, A., Johnson, B., Gardiner, E., Kuhan, G., McCollum, P., …Chetter, I. (2001). Risk modelling for carotid endarterectomy. British journal of surgery, 88(4), 622 - 622. https://doi.org/10.1046/j.1365-2168.2001.01757-62.x