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Investigating mechanisms underpinning the detrimental impact of a high-fat diet in the developing and adult hypermuscular myostatin null mouse (2015)
Journal Article
Matsakas, A., Prosdocimo, D. A., Mitchell, R., Collins-Hooper, H., Giallourou, N., Swann, J. R., …Patel, K. (2015). Investigating mechanisms underpinning the detrimental impact of a high-fat diet in the developing and adult hypermuscular myostatin null mouse. Skeletal muscle, 5(1), doi:10.1186/s13395-015-0063-5. ISSN 2044-5040

© 2015 Matsakas et al. Background: Obese adults are prone to develop metabolic and cardiovascular diseases. Furthermore, over-weight expectant mothers give birth to large babies who also have increased likelihood of developing metabolic and cardiovas... Read More about Investigating mechanisms underpinning the detrimental impact of a high-fat diet in the developing and adult hypermuscular myostatin null mouse.

PGC1β activates an antiangiogenic program to repress neoangiogenesis in muscle ischemia (2014)
Journal Article
Yadav, V., Matsakas, A., Lorca, S., & Narkar, V. A. (2014). PGC1β activates an antiangiogenic program to repress neoangiogenesis in muscle ischemia. Cell reports, 8(3), 783-797. https://doi.org/10.1016/j.celrep.2014.06.040

Revascularization of ischemic skeletalmuscle is governed by a balance between pro- and antiangiogenic factors in multiple cell types but particularly in myocytes and endothelial cells. Whereas the regulators of proangiogenic factors are well defined... Read More about PGC1β activates an antiangiogenic program to repress neoangiogenesis in muscle ischemia.