All Outputs (3)

TRPA1 agonists evoke coughing in guinea pig and human volunteers (2009)
Journal Article
Birrell, M. A., Belvisi, M. G., Grace, M., Sadofsky, L., Faruqi, S., Hele, D. J., Maher, S. A., Freund-Michel, V., & Morice, A. H. (2009). TRPA1 agonists evoke coughing in guinea pig and human volunteers. American Journal of Respiratory and Critical Care Medicine, 180(11), 1042-1047. https://doi.org/10.1164/rccm.200905-0665OC

Rationale: Cough is the most frequent reason for consultation with a family doctor, or with a general or respiratory physician. Treatment options are limited and one meta-analysis concluded that over-the-counter remedies are ineffective. There is als... Read More about TRPA1 agonists evoke coughing in guinea pig and human volunteers.

The online Cough Clinic: Developing guideline-based diagnosis and advice (2009)
Journal Article
Dettmar, P. W., Strugala, V., Fathi, H., Dettmar, H. J., Wright, C., & Morice, A. H. (2009). The online Cough Clinic: Developing guideline-based diagnosis and advice. European respiratory journal, 34(4), 819-824. https://doi.org/10.1183/09031936.00126908

The aim of the present study was make chronic cough guidelines more practical and user friendly by developing an internet-based interactive diagnostic questionnaire for chronic cough. A prospective cohort study of chronic cough sufferers was conducte... Read More about The online Cough Clinic: Developing guideline-based diagnosis and advice.

Combination of sitaxentan and tadalafil for idiopathic pulmonary arterial hypertension following relapse on bosentan (2009)
Journal Article
Faruqi, S., Fathi, H., & Morice, A. H. (2010). Combination of sitaxentan and tadalafil for idiopathic pulmonary arterial hypertension following relapse on bosentan. International journal of cardiology, 144(3), e43-e45. https://doi.org/10.1016/j.ijcard.2008.12.065

Sitaxentan, a highly-selective endothelin receptor antagonist (ETRA) and bosentan a non-selective ETRA are both approved for the treatment of idiopathic pulmonary arterial hypertension (iPAH). Sildenafil is a phosphodiesterase-5 (PDE-5) inhibitor use... Read More about Combination of sitaxentan and tadalafil for idiopathic pulmonary arterial hypertension following relapse on bosentan.