An in vitro multi-organ microphysiological system (MPS) to investigate the gut-to-brain translocation of neurotoxins
(2024)
Journal Article
Jones, E. J., Skinner, B. M., Parker, A., Baldwin, L. R., Greenman, J., Carding, S. R., & Funnell, S. G. (2024). An in vitro multi-organ microphysiological system (MPS) to investigate the gut-to-brain translocation of neurotoxins. Biomicrofluidics, 18(5), Article 054105. https://doi.org/10.1063/5.0200459
The death of dopamine-producing neurons in the substantia nigra in the base of the brain is a defining pathological feature in the development of Parkinson's disease (PD). PD is, however, a multi-systemic disease, also affecting the peripheral nervou...
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