Co-expression of C9orf72 related dipeptide-repeats over 1000 repeat units reveals age-A nd combination-specific phenotypic profiles in Drosophila
(2020)
Journal Article
West, R. J., Sharpe, J. L., Voelzmann, A., Munro, A. L., Hahn, I., Baines, R. A., & Pickering-Brown, S. (2020). Co-expression of C9orf72 related dipeptide-repeats over 1000 repeat units reveals age-A nd combination-specific phenotypic profiles in Drosophila. Acta Neuropathologica Communications, 8(1), Article 158. https://doi.org/10.1186/s40478-020-01028-y
A large intronic hexanucleotide repeat expansion (GGGGCC) within the C9orf72 (C9orf72-SMCR8 Complex Subunit) locus is the most prevalent genetic cause of both Frontotemporal Dementia (FTD) and Motor Neuron Disease (MND). In patients this expansion is... Read More about Co-expression of C9orf72 related dipeptide-repeats over 1000 repeat units reveals age-A nd combination-specific phenotypic profiles in Drosophila.