Murine Creld1 controls cardiac development through activation of calcineurin/NFATc1 signaling
(2014)
Journal Article
Mass, E., Wachten, D., Aschenbrenner, A. C., Voelzmann, A., & Hoch, M. (2014). Murine Creld1 controls cardiac development through activation of calcineurin/NFATc1 signaling. Developmental Cell, 28(6), 711-726. https://doi.org/10.1016/j.devcel.2014.02.012
Calcineurin is a heteromeric Ca2+-dependent serine/threonine phosphatase. It dephosphorylates the transcription factor nuclear factor of activated Tcells (NFAT) in the cytoplasm, which subsequently undergoes nuclear translocation. NFAT regulates nume... Read More about Murine Creld1 controls cardiac development through activation of calcineurin/NFATc1 signaling.