All Outputs (2)

Efa6 protects axons and regulates their growth and branching by inhibiting microtubule polymerisation at the cortex (2019)
Journal Article
Qu, Y., Hahn, I., Lees, M., Parkin, J., Voelzmann, A., Dorey, K., …Prokop, A. (2019). Efa6 protects axons and regulates their growth and branching by inhibiting microtubule polymerisation at the cortex. eLife, 8, Article e50319. https://doi.org/10.7554/eLife.50319

Cortical collapse factors affect microtubule (MT) dynamics at the plasma membrane. They play important roles in neurons, as suggested by inhibition of axon growth and regeneration through the ARF activator Efa6 in C. elegans, and by neurodevelopmenta... Read More about Efa6 protects axons and regulates their growth and branching by inhibiting microtubule polymerisation at the cortex.

The model of local axon homeostasis - Explaining the role and regulation of microtubule bundles in axon maintenance and pathology (2019)
Journal Article
Hahn, I., Voelzmann, A., Liew, Y. T., Costa-Gomes, B., & Prokop, A. (2019). The model of local axon homeostasis - Explaining the role and regulation of microtubule bundles in axon maintenance and pathology. Neural Development, 14(1), Article 11. https://doi.org/10.1186/s13064-019-0134-0

Axons are the slender, cable-like, up to meter-long projections of neurons that electrically wire our brains and bodies. In spite of their challenging morphology, they usually need to be maintained for an organism's lifetime. This makes them key lesi... Read More about The model of local axon homeostasis - Explaining the role and regulation of microtubule bundles in axon maintenance and pathology.