All Outputs (3)

Bisoprolol in Patients With Chronic Obstructive Pulmonary Disease at High Risk of Exacerbation: The BICS Randomized Clinical Trial (2024)
Journal Article
Devereux, G., Cotton, S., Nath, M., McMeekin, N., Campbell, K., Chaudhuri, R., …Lipworth, B. J. (2024). Bisoprolol in Patients With Chronic Obstructive Pulmonary Disease at High Risk of Exacerbation: The BICS Randomized Clinical Trial. Journal of the American Medical Association, https://doi.org/10.1001/jama.2024.8771

Importance: Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide. Observational studies report that β-blocker use may be associated with reduced risk of COPD exacerbations. However, a recent trial repor... Read More about Bisoprolol in Patients With Chronic Obstructive Pulmonary Disease at High Risk of Exacerbation: The BICS Randomized Clinical Trial.

Low-dose oral theophylline combined with inhaled corticosteroids for people with chronic obstructive pulmonary disease and high risk of exacerbations: A rct (2019)
Journal Article
Devereux, G., Cotton, S., Fielding, S., McMeekin, N., Barnes, P. J., Briggs, A., Burns, G., Chaudhuri, R., Chrystyn, H., Davies, L., De Soyza, A., Gompertz, S., Haughney, J., Innes, K., Kaniewska, J., Lee, A., Morice, A., Norrie, J., Sullivan, A., Wilson, A., & Price, D. (2019). Low-dose oral theophylline combined with inhaled corticosteroids for people with chronic obstructive pulmonary disease and high risk of exacerbations: A rct. Health Technology Assessment, 23(37), 1-145. https://doi.org/10.3310/hta23370

Background: Despite widespread use of therapies such as inhaled corticosteroids (ICSs), people with chronic obstructive pulmonary disease (COPD) continue to suffer, have reduced life expectancy and utilise considerable NHS resources. Laboratory inves... Read More about Low-dose oral theophylline combined with inhaled corticosteroids for people with chronic obstructive pulmonary disease and high risk of exacerbations: A rct.

Effect of Theophylline as Adjunct to Inhaled Corticosteroids on Exacerbations in Patients with COPD: A Randomized Clinical Trial (2018)
Journal Article
Devereux, G., Cotton, S., Fielding, S., McMeekin, N., Barnes, P. J., Briggs, A., Burns, G., Chaudhuri, R., Chrystyn, H., Davies, L., De Soyza, A., Gompertz, S., Haughney, J., Innes, K., Kaniewska, J., Lee, A., Morice, A., Norrie, J., Sullivan, A., Wilson, A., & Price, D. (2018). Effect of Theophylline as Adjunct to Inhaled Corticosteroids on Exacerbations in Patients with COPD: A Randomized Clinical Trial. Journal of the American Medical Association, 320(15), 1548-1559. https://doi.org/10.1001/jama.2018.14432

© 2018 American Medical Association. All rights reserved. Importance: Chronic obstructive pulmonary disease (COPD) is a major global health issue and theophylline is used extensively. Preclinical investigations have demonstrated that low plasma conce... Read More about Effect of Theophylline as Adjunct to Inhaled Corticosteroids on Exacerbations in Patients with COPD: A Randomized Clinical Trial.