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Managing constipation in adults with co-morbidities (2016)
Journal Article
Gardiner, A., & Hilton, A. (2016). Managing constipation in adults with co-morbidities. Independent nurse, 2016(10), 21-25 . https://doi.org/10.12968/indn.2016.10.21

Constipation can be described in a number of ways but in general it is related to straining, reduced frequency of defecation and/or a sensation of incomplete bowel emptying. The ability of the bowel to empty is related to the effectiveness of colonic... Read More about Managing constipation in adults with co-morbidities.

Identifying patient problems and devising care pathways with the neurogenic bowel dysfunction score (2014)
Journal Article
Gardiner, A., & Wallace, E. (2014). Identifying patient problems and devising care pathways with the neurogenic bowel dysfunction score. Gastrointestinal Nursing, 12(Sup2), S17-S23. https://doi.org/10.12968/gasn.2014.12.Sup2.S17

© MA Healthcare Limited 2014. Neurogenic bowel dysfunction (NBD) is a consequence of dysfunction of the autonomic nervous system leading to impairment of sensory and/or motor control; it includes constipation, incontinence, and disordered defaecation... Read More about Identifying patient problems and devising care pathways with the neurogenic bowel dysfunction score.

Artificial neural networks to predict presence of significant pathology in patients presenting to routine colorectal clinics (2010)
Journal Article
Maslekar, S., Gardiner, A. B., Monson, J. R. T., & Duthie, G. S. (2010). Artificial neural networks to predict presence of significant pathology in patients presenting to routine colorectal clinics. Colorectal Disease, 12(12), 1254-1259. doi:10.1111/j.1463-1318.2009.02005.x

Aim Artificial neural networks (ANNs) are computer programs used to identify complex relations within data. Routine predictions of presence of colorectal pathology based on population statistics have little meaning for individual patient. This result... Read More about Artificial neural networks to predict presence of significant pathology in patients presenting to routine colorectal clinics.

Randomized controlled trial of patient-controlled sedation for colonoscopy: Entonox vs modified patient-maintained target-controlled propofol (2009)
Journal Article
Maslekar, S., Balaji, P., Gardiner, A., Culbert, B., Monson, J. R., & Duthie, G. S. (2011). Randomized controlled trial of patient-controlled sedation for colonoscopy: Entonox vs modified patient-maintained target-controlled propofol. Colorectal Disease, 13(1), 48-57. doi:10.1111/j.1463-1318.2009.01988.x

Aim Propofol sedation is often associated with deep sedation and decreased manoeuvrability. Patient-maintained sedation has been used in such patients with minimal side-effects. We aimed to compare novel modified patient-maintained target-controlled... Read More about Randomized controlled trial of patient-controlled sedation for colonoscopy: Entonox vs modified patient-maintained target-controlled propofol.

Patient satisfaction with lower gastrointestinal endoscopy: doctors, nurse and nonmedical endoscopists (2009)
Journal Article
Maslekar, S., Hughes, M., Gardiner, A., Monson, J. R. T., & Duthie, G. S. (2010). Patient satisfaction with lower gastrointestinal endoscopy: doctors, nurse and nonmedical endoscopists. Colorectal disease, 12(10), 1033-1038. https://doi.org/10.1111/j.1463-1318.2009.01989.x

Aim Assessment of patient satisfaction with lower gastrointestinal endoscopy (LGE) comprising colonoscopy and flexible sigmoidoscopy is gaining increasing importance. We have now trained non healthcare professionals such as nonmedical endoscopists (N... Read More about Patient satisfaction with lower gastrointestinal endoscopy: doctors, nurse and nonmedical endoscopists.

Randomized clinical trial of Entonox versus midazolam-fentanyl sedation for colonoscopy (2009)
Journal Article
Maslekar, S., Gardiner, A., & Duthie, G. (2009). Randomized clinical trial of Entonox versus midazolam-fentanyl sedation for colonoscopy. British journal of surgery, 96(4), 361 - 368. https://doi.org/10.1002/bjs.6467

BACKGROUND Intravenous sedation for colonoscopy is associated with cardiorespiratory complications and delayed recovery. The aim of this randomized clinical trial was to compare the efficacy of Entonox (50 per cent nitrous oxide and 50 per cent oxyge... Read More about Randomized clinical trial of Entonox versus midazolam-fentanyl sedation for colonoscopy.

Randomized clinical trial of Entonox ® versus midazolam-fentanyl sedation for colonoscopy (2009)
Journal Article
Maslekar, S., Gardiner, A., Hughes, M., Culbert, B., & Duthie, G. S. (2009). Randomized clinical trial of Entonox ® versus midazolam-fentanyl sedation for colonoscopy. British journal of surgery : BJS, 96(4), 361-368. doi:10.1002/bjs.6467

Background: Intravenous sedation for colonoscopy is associated with cardiorespiratory complications and delayed recovery. The aim of this randomized clinical trial was to compare the efficacy of Entonox ® (50 per cent nitrous oxide and 50 per cent o... Read More about Randomized clinical trial of Entonox ® versus midazolam-fentanyl sedation for colonoscopy.

Results of the United Kingdoms first pilot study for nonmedical endoscopy practitioners (2008)
Journal Article
Gardiner, A. B. (2009). Results of the United Kingdoms first pilot study for nonmedical endoscopy practitioners. Colorectal Disease, 11(2), 208-214. doi:10.1111/j.1463-1318.2008.01555.x

Spencer and Ready published the first description of nonmedically qualified endoscopists in 1977 [Dis Colon Rectum 1977; 20: 94]. Since then there has been an explosion of interest in this concept. Duthie et al. [Gut 1998; 43: 711] first described Nu... Read More about Results of the United Kingdoms first pilot study for nonmedical endoscopy practitioners.

Anterior anal sphincter repair for fecal incontinence: Good longterm results are possible (2006)
Journal Article
Maslekar, S., Gardiner, A. B., & Duthie, G. S. (2007). Anterior anal sphincter repair for fecal incontinence: Good longterm results are possible. Journal of The American College of Surgeons, 204(1), (40-46). doi:10.1016/j.jamcollsurg.2006.10.008. ISSN 1072-7515

Background: Anterior anal sphincter repair (ASR) is standard treatment for fecal incontinence resulting from an obstetrically damaged anal sphincter. Longterm results of repair have generally been shown to be poor. This review of single-unit series a... Read More about Anterior anal sphincter repair for fecal incontinence: Good longterm results are possible.

A new method of assessing anal sphincter integrity using inverted vectormanometry (2006)
Journal Article
Kaur, G., Gardiner, A., & Duthie, G. S. (2006). A new method of assessing anal sphincter integrity using inverted vectormanometry. Diseases of the colon & rectum, 49(8), 1160-1166. doi:10.1007/s10350-006-0556-8

PURPOSE: Vectorgraphy as an integrated mapping of radial pressure profiles of the anal canal has been used to attempt identification of pressure-related defects with doubtful reliability since vectorgraphs bear no resemblance to endoanal ultrasound s... Read More about A new method of assessing anal sphincter integrity using inverted vectormanometry.

Investigation and treatment of faecal incontinence (2006)
Journal Article
Maslekar, S., Gardiner, A., Maklin, C., & Duthie, G. S. (2006). Investigation and treatment of faecal incontinence. Postgraduate Medical Journal, 82(968), 363-371. doi:10.1136/pgmj.2005.044099

Faecal incontinence is a debilitating condition affecting people of all ages, and significantly impairs quality of life. Proper clinical assessment followed by conservative medical therapy leads to improvement in more than 50% of cases, including pat... Read More about Investigation and treatment of faecal incontinence.

Randomised controlled trial of sedation for colonoscopy: Entonox versus intravenous sedation (2006)
Journal Article
Maslekar, S. K., Hughes, M., Skinn, E., Gardiner, A., Culbert, B., & Duthie, G. S. (2006). Randomised controlled trial of sedation for colonoscopy: Entonox versus intravenous sedation. Gastrointestinal Endoscopy, 63(5), AB97. doi:10.1016/j.gie.2006.03.087

Introduction: Intravenous sedation for colonoscopy is associated with cardio-respiratory complications, delayed recovery and prolonged drowsiness. We aimed to determine whether inhaled Entonox

Non-medical colonoscopy (2006)
Journal Article
Maslekar, S. K., Gardiner, A., Hughes, M., & Duthie, G. S. (2006). Non-medical colonoscopy. Gastrointestinal Endoscopy, 63(5), AB114. doi:10.1016/j.gie.2006.03.148

Aims: There is increasing demand for colonoscopy especially with introduction of screening programmes. Though colonoscopy is performed by doctors and nurses, there is an acute shortage of trained colonoscopists


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