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All Outputs (2)

Food restriction reverses the hyper-muscular phenotype and force generation capacity deficit of the myostatin null mouse (2012)
Journal Article
Matsakas, A., Romanello, V., Sartori, R., Masiero, E., Macharia, R., Otto, A., …Patel, K. (2013). Food restriction reverses the hyper-muscular phenotype and force generation capacity deficit of the myostatin null mouse. International journal of sports medicine, 34(3), 223-231. https://doi.org/10.1055/s-0032-1312605

Food restriction has a great impact on skeletal muscle mass by inducing muscle protein breakdown to provide substrates for energy production through gluconeogenesis. Genetic models of hyper-muscularity interfere with the normal balance between protei... Read More about Food restriction reverses the hyper-muscular phenotype and force generation capacity deficit of the myostatin null mouse.

Revascularization of ischemic skeletal muscle by estrogen-related receptor-gamma (2012)
Journal Article
Matsakas, A., Yadav, V., Lorca, S., Evans, R., & Narkar, V. (2012). Revascularization of ischemic skeletal muscle by estrogen-related receptor-gamma. Circulation Research, 110(8), 1087-1096. https://doi.org/10.1161/CIRCRESAHA.112.266478

RATIONALE Oxidative myofibers in the skeletal muscles express high levels of angiogenic factors, have dense vasculature, and promptly revascularize during ischemia. Estrogen-related receptor-gamma (ERRγ) activates genes that govern metabolic and vasc... Read More about Revascularization of ischemic skeletal muscle by estrogen-related receptor-gamma.