All Outputs (5)

Retrospective Medical Record Research: Reflections of A Unsponsored Researcher (2019)
Journal Article
Bature, F., Guinn, B., Vseteckova, J., Pang, D., & Pappas, Y. (2019). Retrospective Medical Record Research: Reflections of A Unsponsored Researcher. Biomedical Journal of Scientific & Technical Research, 21(4), 16080-16086. https://doi.org/10.26717/BJSTR.2019.21.003642

This article is a reflective narrative by the author following the successful completion of a doctoral thesis involving the analysis of primary care data. The aim of the study was to identify patterns in signs and symptoms preceding a clinical diagno... Read More about Retrospective Medical Record Research: Reflections of A Unsponsored Researcher.

Investigating the role of CBX2 in models of triple negative breast cancer (2019)
Thesis
Warren, C. (2019). Investigating the role of CBX2 in models of triple negative breast cancer. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4222872

Breast cancer accounts for around 11,500 deaths per year in the UK in women. There are several subtypes of breast cancer including triple negative breast cancer (TNBC) which is categorised by a lack of oestrogen, progesterone and human epidermal grow... Read More about Investigating the role of CBX2 in models of triple negative breast cancer.

Exploring the role of metals and senescence in cutaneous wound repair (2019)
Thesis
Wilkinson, H. N. (2019). Exploring the role of metals and senescence in cutaneous wound repair. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4227385

Acute wound healing involves a tightly regulated cascade of cellular signalling and functional events. Deterioration at any stage of this sophisticated system can lead to healing impairment and chronic, non-healing wounds. Chronic wounds, which are p... Read More about Exploring the role of metals and senescence in cutaneous wound repair.

Urine biomarkers for the early detection of ovarian cancer – are we there yet? (2019)
Journal Article
Grayson, K., Gregory, E., Khan, G., & Guinn, B.-A. (2019). Urine biomarkers for the early detection of ovarian cancer – are we there yet?. Biomarkers in Cancer, 11, Article 1983097. https://doi.org/10.1177/1179299x19830977

Ovarian cancer affects around 7500 women in the United Kingdom every year. Despite this, there is no effective screening strategy or standard treatment for ovarian cancer. If diagnosed during stage I, ovarian cancer has a 90% 5-year survival rate; ho... Read More about Urine biomarkers for the early detection of ovarian cancer – are we there yet?.

Antigenic targets for the immunotherapy of acute myeloid leukaemia (2019)
Journal Article
Khan, G., Orchard, K., & Guinn, B. A. (2019). Antigenic targets for the immunotherapy of acute myeloid leukaemia. Journal of Clinical Medicine, 8(2), 134. https://doi.org/10.3390/jcm8020134

One of the most promising approaches to preventing relapse is the stimulation of the body’s own immune system to kill residual cancer cells after conventional therapy has destroyed the bulk of the tumour. In acute myeloid leukaemia (AML), the high fr... Read More about Antigenic targets for the immunotherapy of acute myeloid leukaemia.