Sigma-1 receptors modulate neonatal Nav1.5 ion channels in breast cancer cell lines
(2016)
Journal Article
Aydar, E., Stratton, D., Fraser, S. P., Djamgoz, M. B., & Palmer, C. (2016). Sigma-1 receptors modulate neonatal Nav1.5 ion channels in breast cancer cell lines. European Biophysics Journal, 45(7), 671-683. https://doi.org/10.1007/s00249-016-1135-0
The main aim of this study was to investigate a possible functional connection between sigma-1 receptors and voltage-gated sodium channels (VGSCs) in human breast cancer cells. The hypothesis was that sigma-1 drugs could alter the metastatic properti... Read More about Sigma-1 receptors modulate neonatal Nav1.5 ion channels in breast cancer cell lines.