All Outputs (64)

The automated monocyte count is independently predictive of overall survival from diagnosis in chronic lymphocytic leukaemia and of survival following first-line chemotherapy (2013)
Journal Article
Mazumdar, R., Evans, P., Culpin, R., Bailey, J., & Allsup, D. (2013). The automated monocyte count is independently predictive of overall survival from diagnosis in chronic lymphocytic leukaemia and of survival following first-line chemotherapy. Leukemia Research, 37(6), 614-618. https://doi.org/10.1016/j.leukres.2013.02.020

We conducted an analysis of the effect of monocytosis at diagnosis of CLL on subsequent overall (OS) and treatment-free survival (TFS). Monocyte counts were performed using the Sysmex XE2100™ analyser. A monocyte count >0.91×109L-1 at the time of dia... Read More about The automated monocyte count is independently predictive of overall survival from diagnosis in chronic lymphocytic leukaemia and of survival following first-line chemotherapy.

Increased inducible heat shock protein 72 expression associated with PBMC isolated from patients with haematological tumours (2012)
Journal Article
Madden, L. A., Hayman, Y. A., Underwood, C., Vince, R. V., Greenman, J., Allsup, D., & Ali, S. (2012). Increased inducible heat shock protein 72 expression associated with PBMC isolated from patients with haematological tumours. Scandinavian journal of clinical & laboratory investigation, 72(5), 380-386. https://doi.org/10.3109/00365513.2012.681683

Background. Heat shock protein 72 (Hsp72) is a highly inducible stress protein and molecular chaperone. Cancers have been shown to be associated with increased Hsp72 expression within the tumour itself and this may lead to resistance to apoptosis. Me... Read More about Increased inducible heat shock protein 72 expression associated with PBMC isolated from patients with haematological tumours.

Chronic lymphocytic leukaemia is a risk factor for venous thromboembolism (2010)
Journal Article
Whittle, A. M., Allsup, D. J., & Bailey, J. R. (2011). Chronic lymphocytic leukaemia is a risk factor for venous thromboembolism. Leukemia Research, 35(3), 419-421. https://doi.org/10.1016/j.leukres.2010.11.011

Venous thromboembolism (VTE) is a major cause of morbidity and mortality in cancer patients. The literature is sparse on the incidence in the most common lymphoid malignancy, chronic lymphocytic leukaemia (CLL). We calculated the incidence rates for... Read More about Chronic lymphocytic leukaemia is a risk factor for venous thromboembolism.

Thalidomide enhances cyclophosphamide and dexamethasone-mediated cytotoxicity towards cultured chronic lymphocytic leukaemia cells (2010)
Journal Article
Pointon, J. C., Eagle, G., Bailey, J., Evans, P., Allsup, D., & Greenman, J. (2010). Thalidomide enhances cyclophosphamide and dexamethasone-mediated cytotoxicity towards cultured chronic lymphocytic leukaemia cells. Oncology Reports, 24(5), 1315-1321. https://doi.org/10.3892/or_00000988

Numerous chemotherapeutic regimens exist for the treatment of symptomatic or progressive chronic lymphocytic leukaemia (CLL). However, once the disease becomes refractory to nucleoside-based therapy the prognosis is poor. In this study we investigate... Read More about Thalidomide enhances cyclophosphamide and dexamethasone-mediated cytotoxicity towards cultured chronic lymphocytic leukaemia cells.