T cell exhaustion potential of bacterial superantigens relevant in severe infections and cancer
(2023)
Thesis
Tantoush, F. A. A. (2023). T cell exhaustion potential of bacterial superantigens relevant in severe infections and cancer. (Thesis). University of Hull. https://hull-repository.worktribe.com/output/4373985
Bacterial superantigens (SAgs) trigger oligoclonal activation of T cells by crosslinking MHC-class-II, on Ag-presenting cells, to the T cell receptor (TCR)/CD28, on T cells, which can be independent of Lck, a critical kinase normally involved... Read More about T cell exhaustion potential of bacterial superantigens relevant in severe infections and cancer.