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All Outputs (149)

Palliative medicine in the intensive care unit: needs, delivery, quality (2021)
Journal Article
Hill, S., Dawood, A., Boland, E., Leahy, H. E., & Murtagh, F. (in press). Palliative medicine in the intensive care unit: needs, delivery, quality. BMJ supportive & palliative care, Article 2795. https://doi.org/10.1136/bmjspcare-2020-002795

Background: 15%-20% of critical care patients die during their hospital admission. This service evaluation assesses quality of palliative care in intensive care units (ICUs) compared with national standards. Methods: Retrospective review of records f... Read More about Palliative medicine in the intensive care unit: needs, delivery, quality.

Socioeconomic position and use of hospital-based care towards the end of life: a mediation analysis using the English Longitudinal Study of Ageing (2021)
Journal Article
Davies, J. M., Maddocks, M., Chua, K. C., Demakakos, P., Sleeman, K. E., & Murtagh, F. E. (2021). Socioeconomic position and use of hospital-based care towards the end of life: a mediation analysis using the English Longitudinal Study of Ageing. The Lancet. Public Health, 6(3), e155-e163. https://doi.org/10.1016/S2468-2667%2820%2930292-9

© 2021 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license Background: Many patients prefer to avoid hospital-based care towards the end of life, yet hospitalisation is common and more likely for peopl... Read More about Socioeconomic position and use of hospital-based care towards the end of life: a mediation analysis using the English Longitudinal Study of Ageing.

The challenges of caring for people dying from COVID-19: a multinational, observational study (CovPall) (2021)
Journal Article
Oluyase, A. O., Hocaoglu, M., Cripps, R. L., Maddocks, M., Walshe, C., Fraser, L. K., Preston, N., Dunleavy, L., Bradshaw, A., Murtagh, F. E., Bajwah, S., Sleeman, K. E., & Higginson, I. J. (in press). The challenges of caring for people dying from COVID-19: a multinational, observational study (CovPall). Journal of pain and symptom management, https://doi.org/10.1016/j.jpainsymman.2021.01.138

Context: Systematic data on the care of people dying with COVID-19 are scarce. Objectives: To understand the response of and challenges faced by palliative care services during the COVID-19 pandemic, and identify associated factors. Methods: We surve... Read More about The challenges of caring for people dying from COVID-19: a multinational, observational study (CovPall).

Implementing person-centred outcome measures in palliative care: An exploratory qualitative study using Normalisation Process Theory to understand processes and context (2020)
Journal Article
Bradshaw, A., Santarelli, M., Mulderrig, M., Khamis, A., Sartain, K., Boland, J. W., Bennett, M. I., Johnson, M., Pearson, M., & Murtagh, F. E. (in press). Implementing person-centred outcome measures in palliative care: An exploratory qualitative study using Normalisation Process Theory to understand processes and context. Palliative medicine, https://doi.org/10.1177/0269216320972049

© The Author(s) 2020. Background: Despite evidence demonstrating the utility of using Person-Centred Outcome Measures within palliative care settings, implementing them into routine practice is challenging. Most research has described barriers to, wi... Read More about Implementing person-centred outcome measures in palliative care: An exploratory qualitative study using Normalisation Process Theory to understand processes and context.

Nurse-led advance care planning with older people who have end-stage kidney disease: feasibility of a deferred entry randomised controlled trial incorporating an economic evaluation and mixed methods process evaluation (ACReDiT) (2020)
Journal Article
O’Halloran, P., Noble, H., Norwood, K., Maxwell, P., Murtagh, F., Shields, J., Mullan, R., Matthews, M., Cardwell, C., Clarke, M., Morton, R., Shah, K., Forbes, T., & Brazil, K. (2020). Nurse-led advance care planning with older people who have end-stage kidney disease: feasibility of a deferred entry randomised controlled trial incorporating an economic evaluation and mixed methods process evaluation (ACReDiT). BMC Nephrology, 21, Article 478. https://doi.org/10.1186/s12882-020-02129-5

© 2020, The Author(s).
Background: Advance Care Planning is recommended for people with end-stage kidney disease but evidence is limited. Robust clinical trials are needed to investigate the impact of advance care planning in this population. There... Read More about Nurse-led advance care planning with older people who have end-stage kidney disease: feasibility of a deferred entry randomised controlled trial incorporating an economic evaluation and mixed methods process evaluation (ACReDiT).

The effectiveness and cost-effectiveness of hospital-based specialist palliative care for adults with advanced illness and their caregivers (2020)
Journal Article
Bajwah, S., Oluyase, A. O., Yi, D., Gao, W., Evans, C. J., Grande, G., Todd, C., Costantini, M., Murtagh, F. E., & Higginson, I. J. (2020). The effectiveness and cost-effectiveness of hospital-based specialist palliative care for adults with advanced illness and their caregivers. The Cochrane database of systematic reviews, 2020(9), Article CD012780. https://doi.org/10.1002/14651858.CD012780.pub2

Background
Serious illness is often characterised by physical/psychological problems, family support needs, and high healthcare resource use. Hospital‐based specialist palliative care (HSPC) has developed to assist in better meeting the needs of pat... Read More about The effectiveness and cost-effectiveness of hospital-based specialist palliative care for adults with advanced illness and their caregivers.

The stability of care preferences following acute illness: a mixed methods prospective cohort study of frail older people (2020)
Journal Article
Etkind, S., Lovell, N., Bone, A., Guo, P., Nicholson, C., Murtagh, F. E., & Higginson, I. J. (2020). The stability of care preferences following acute illness: a mixed methods prospective cohort study of frail older people. BMC Geriatrics, 20(1), Article 370. https://doi.org/10.1186/s12877-020-01725-2

Background: Patient preferences are integral to person-centred care, but preference stability is poorly understood in older people, who may experience fluctuant illness trajectories with episodes of acute illness. We aimed to describe, and explore in... Read More about The stability of care preferences following acute illness: a mixed methods prospective cohort study of frail older people.

The Prepare for Kidney Care Study: prepare for renal dialysis versus responsive management in advanced chronic kidney disease (2020)
Journal Article
Murphy, E., Burns, A., Murtagh, F. E., Rooshenas, L., & Caskey, F. J. (2021). The Prepare for Kidney Care Study: prepare for renal dialysis versus responsive management in advanced chronic kidney disease. Nephrology Dialysis Transplantation, 36(6), 975-982. https://doi.org/10.1093/ndt/gfaa209

Shared decision making in advanced chronic kidney disease (CKD) requires unbiased information on survival and person-centred outcomes known to matter to patients: quality of life, symptom burden and support from family and healthcare professionals. T... Read More about The Prepare for Kidney Care Study: prepare for renal dialysis versus responsive management in advanced chronic kidney disease.

Implementation of a complex intervention to improve care for patients whose situations are clinically uncertain in hospital settings: A multi-method study using normalisation process theory (2020)
Journal Article
Johnson, H., Yorganci, E., Evans, C. J., Barclay, S., Murtagh, F. E., Yi, D., Gao, W., Sampson, E. L., Droney, J., Farquhar, M., & Koffman, J. (2020). Implementation of a complex intervention to improve care for patients whose situations are clinically uncertain in hospital settings: A multi-method study using normalisation process theory. PLoS ONE, 15(9), Article e0239181. https://doi.org/10.1371/journal.pone.0239181

PURPOSE: To examine the use of Normalisation Process Theory (NPT) to establish if, and in what ways, the AMBER care bundle can be successfully normalised into acute hospital practice, and to identify necessary modifications to optimise its implementa... Read More about Implementation of a complex intervention to improve care for patients whose situations are clinically uncertain in hospital settings: A multi-method study using normalisation process theory.

International variation in dialysis discontinuation in patients with advanced kidney disease (2020)
Journal Article
Jassal, S. V., Larkina, M., Jager, K. J., Murtagh, F. E., O’Hare, A. M., Hanafusa, N., Morgenstern, H., Port, F. K., McCullough, K., Pisoni, R., Tentori, F., Perlman, R., & Swartz, R. D. (2020). International variation in dialysis discontinuation in patients with advanced kidney disease. Canadian Medical Association Journal, 192(35), E995-E1002. https://doi.org/10.1503/cmaj.191631

BACKGROUND: Decisions about dialysis for advanced kidney disease are often strongly shaped by sociocultural and system-level factors rather than the priorities and values of individual patients. We examined international variation in the uptake of co... Read More about International variation in dialysis discontinuation in patients with advanced kidney disease.

Health of mothers of children with a life-limiting condition: a protocol for comparative cohort study using the Clinical Practice Research Datalink (2020)
Journal Article
Fraser, L. K., Murtagh, F. E., Sheldon, T., Gilbody, S., & Hewitt, C. (2020). Health of mothers of children with a life-limiting condition: a protocol for comparative cohort study using the Clinical Practice Research Datalink. BMJ open, 10(7), Article e034024. https://doi.org/10.1136/bmjopen-2019-034024

INTRODUCTION: There are now nearly 50 000 children with a life-limiting or life-threatening condition in the UK. These include conditions where there is no reasonable hope of cure and from which they will die, as well as conditions for which curative... Read More about Health of mothers of children with a life-limiting condition: a protocol for comparative cohort study using the Clinical Practice Research Datalink.

The development and cognitive testing of the positive outcomes HIV PROM: A brief novel patient-reported outcome measure for adults living with HIV (2020)
Journal Article
Bristowe, K., Murtagh, F. E., Clift, P., James, R., Josh, J., Platt, M., Whetham, J., Nixon, E., Post, F. A., McQuillan, K., Cheallaigh, C. N., Kall, M., Anderson, J., Sullivan, A. K., & Harding, R. (2020). The development and cognitive testing of the positive outcomes HIV PROM: A brief novel patient-reported outcome measure for adults living with HIV. Health and quality of life outcomes, 18(1), Article 214. https://doi.org/10.1186/s12955-020-01462-5

© 2020 The Author(s). Background: People living with HIV experience burdensome multidimensional symptoms and concerns requiring person-centred care. Routine use of patient reported outcome measures can improve outcomes. There is no brief patient repo... Read More about The development and cognitive testing of the positive outcomes HIV PROM: A brief novel patient-reported outcome measure for adults living with HIV.

Development of a core outcome set to use in the research and assessment of malignant bowel obstruction: protocol for the RAMBO study (2020)
Journal Article
Baddeley, E., Bravington, A., Johnson, M., Currow, D., Murtagh, F. E., Boland, E., Obita, G., Nelson, A., Seddon, K., Oliver, A., Noble, S., & Boland, J. (2020). Development of a core outcome set to use in the research and assessment of malignant bowel obstruction: protocol for the RAMBO study. BMJ open, 10(6), Article 039154. https://doi.org/10.1136/bmjopen-2020-039154

INTRODUCTION: Studies regarding the management of malignant bowel obstruction (MBO) report conflicting findings. This is partly due to different outcome measures being used to evaluate severity of MBO and the response to treatments. Furthermore, curr... Read More about Development of a core outcome set to use in the research and assessment of malignant bowel obstruction: protocol for the RAMBO study.

Identification of patients with potential palliative care needs: a systematic review of screening tools in primary care (2020)
Journal Article
ElMokhallalati, Y., Bradley, S. H., Chapman, E., Ziegler, L., Murtagh, F. E., Johnson, M. J., & Bennett, M. I. (2020). Identification of patients with potential palliative care needs: a systematic review of screening tools in primary care. Palliative medicine, 34(8), 989-1005. https://doi.org/10.1177/0269216320929552

Background
Despite increasing evidence of the benefits of early access to palliative care, many patients do not receive palliative care in a timely manner. A systematic approach in primary care can facilitate earlier identification of patients with... Read More about Identification of patients with potential palliative care needs: a systematic review of screening tools in primary care.

Quality of life among caregivers of people with end-stage kidney disease managed with dialysis or comprehensive conservative care (2020)
Journal Article
Shah, K. K., Murtagh, F. E., McGeechan, K., Crail, S. M., Burns, A., & Morton, R. L. (2020). Quality of life among caregivers of people with end-stage kidney disease managed with dialysis or comprehensive conservative care. BMC Nephrology, 21(1), 160. https://doi.org/10.1186/s12882-020-01830-9

BACKGROUND: To measure health-related and care-related quality of life among informal caregivers of older people with end-stage kidney disease (ESKD), and to determine the association between caregiver quality of life and care recipient's treatment t... Read More about Quality of life among caregivers of people with end-stage kidney disease managed with dialysis or comprehensive conservative care.

Understanding usual care in randomised controlled trials of complex interventions: A multi-method approach (2020)
Journal Article
Yorganci, E., Evans, C. J., Johnson, H., Barclay, S., Murtagh, F. E., Yi, D., Gao, W., Pickles, A., & Koffman, J. (2020). Understanding usual care in randomised controlled trials of complex interventions: A multi-method approach. Palliative medicine, https://doi.org/10.1177/0269216320905064

Background Evaluations of complex interventions compared to usual care provided in palliative care are increasing. Not describing usual care may affect the interpretation of an intervention’s effectiveness, yet how it can be described remains unclear... Read More about Understanding usual care in randomised controlled trials of complex interventions: A multi-method approach.

Towards person-centred quality care for children with life-limiting and life-threatening illness: Self-reported symptoms, concerns and priority outcomes from a multi-country qualitative study (2020)
Journal Article
Namisango, E., Bristowe, K., Murtagh, F. E., Downing, J., Powell, R. A., Abas, M., Lohfeld, L., Ali, Z., Atieno, M., Haufiku, D., Guma, S., Luyirika, E. B., Mwangi-Powell, F. N., Higginson, I. J., & Harding, R. (2020). Towards person-centred quality care for children with life-limiting and life-threatening illness: Self-reported symptoms, concerns and priority outcomes from a multi-country qualitative study. Palliative medicine, 34(3), 319-335. https://doi.org/10.1177/0269216319900137

© The Author(s) 2020. Background: Paediatric life-limiting and life-threatening conditions (life-limiting conditions) place significant strain on children, families and health systems. Given high service use among this population, it is essential tha... Read More about Towards person-centred quality care for children with life-limiting and life-threatening illness: Self-reported symptoms, concerns and priority outcomes from a multi-country qualitative study.

Supportive care for end-stage kidney disease: an integral part of kidney services across a range of income settings around the world (2020)
Journal Article
Hole, B., Hemmelgarn, B., Brown, E., Brown, M., McCulloch, M. I., Zuniga, C., Andreoli, S. P., Blake, P. G., Couchoud, C., Cueto-Manzano, A. M., Dreyer, G., Garcia Garcia, G., Jager, K. J., McKnight, M., Morton, R. L., Murtagh, F. E., Naicker, S., Obrador, G. T., Perl, J., Rahman, M., …Caskey, F. J. (2020). Supportive care for end-stage kidney disease: an integral part of kidney services across a range of income settings around the world. Kidney International Supplements, 10(1), e86-e94. https://doi.org/10.1016/j.kisu.2019.11.008

© 2020 International Society of Nephrology A key component of treatment for all people with advanced kidney disease is supportive care, which aims to improve quality of life and can be provided alongside therapies intended to prolong life, such as di... Read More about Supportive care for end-stage kidney disease: an integral part of kidney services across a range of income settings around the world.

Considerations on equity in management of end-stage kidney disease in low- and middle-income countries (2020)
Journal Article
Van Biesen, W., Jha, V., Abu-Alfa, A. K., Andreoli, S. P., Ashuntantang, G., Bernieh, B., …Garcia Garcia, G. (2020). Considerations on equity in management of end-stage kidney disease in low- and middle-income countries. Kidney International Supplements, 10(1), e63-e71. https://doi.org/10.1016/j.kisu.2019.11.004

Achievement of equity in health requires development of a health system in which everyone has a fair opportunity to attain their full health potential. The current, large country-level variation in the reported incidence and prevalence of treated end... Read More about Considerations on equity in management of end-stage kidney disease in low- and middle-income countries.