All Outputs (4)

T cell exhaustion potential of bacterial superantigens relevant in severe infections and cancer (2023)
Thesis
Tantoush, F. A. A. T cell exhaustion potential of bacterial superantigens relevant in severe infections and cancer. (Thesis). University of Hull. https://hull-repository.worktribe.com/output/4373985

Bacterial superantigens (SAgs) trigger oligoclonal activation of T cells by crosslinking MHC-class-II, on Ag-presenting cells, to the T cell receptor (TCR)/CD28, on T cells, which can be independent of Lck, a critical kinase normally involved... Read More about T cell exhaustion potential of bacterial superantigens relevant in severe infections and cancer.

Identification and functional characterisation of putative mitochondrial nucleotide transporters from the human pathogen Trypanosome brucei (2018)
Thesis
Alshegifi, M. (2018). Identification and functional characterisation of putative mitochondrial nucleotide transporters from the human pathogen Trypanosome brucei. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4221223

Trypanosoma brucei is a medically important protozoan parasite that causes African sleeping sickness in humans. Although disease treatment is possible, it is hindered by the limited availability of effective drugs and the rapid emergence of drug resi... Read More about Identification and functional characterisation of putative mitochondrial nucleotide transporters from the human pathogen Trypanosome brucei.

Identification and functional characterization of putative mitochondrial iron transporters from the human pathogen Trypanosoma brucei (2017)
Thesis
Zheng, F. (2017). Identification and functional characterization of putative mitochondrial iron transporters from the human pathogen Trypanosoma brucei. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4221817

Trypanosoma brucei is a medically important protozoan parasite causing African sleeping sickness in humans. Treatment of this disease is possible, but is hindered by the limited availability of effective drugs as well as the rapid emergence of drug r... Read More about Identification and functional characterization of putative mitochondrial iron transporters from the human pathogen Trypanosoma brucei.

Mitochondrial ATP production and energy-buffering in the human pathogen Trypanosoma brucei (2013)
Thesis
Gao, F. (2013). Mitochondrial ATP production and energy-buffering in the human pathogen Trypanosoma brucei. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4215678

The mitochondrion plays a vital role in the cellular energy (ATP) provision of the human pathogen Trypanosoma brucei. ATP is produced in the mitochondrial matrix from ADP and inorganic phosphate by substrate-level and oxidative phosphorylation. To ma... Read More about Mitochondrial ATP production and energy-buffering in the human pathogen Trypanosoma brucei.