Toll-like receptor 7 deficiency suppresses type 1 diabetes development by modulating B-cell differentiation and function
(2021)
Journal Article
Huang, J., Peng, J., Pearson, J. A., Efthimiou, G., Hu, Y., Tai, N., …Wen, L. (2021). Toll-like receptor 7 deficiency suppresses type 1 diabetes development by modulating B-cell differentiation and function. Cellular and Molecular Immunology, 18(2), 328-338. https://doi.org/10.1038/s41423-020-00590-8
Innate immunity mediated by Toll-like receptors (TLRs), which can recognize pathogen molecular patterns, plays a critical role in type 1 diabetes development. TLR7 is a pattern recognition receptor that senses single-stranded RNAs from viruses and ho... Read More about Toll-like receptor 7 deficiency suppresses type 1 diabetes development by modulating B-cell differentiation and function.