All Outputs (3)

How to study basement membrane stiffness as a biophysical trigger in prostate cancer and other age-related pathologies or metabolic diseases (2016)
Journal Article
Rodriguez-Teja, M., Breit, C., Clarke, M., Talar, K., Wang, K., Mohammad, M. A., Pickwell, S., Etchandy, G., Stasiuk, G. J., & Sturge, J. (2016). How to study basement membrane stiffness as a biophysical trigger in prostate cancer and other age-related pathologies or metabolic diseases. Journal of visualized experiments : JoVE, 2016(115), https://doi.org/10.3791/54230

Here we describe a protocol that can be used to study the biophysical microenvironment related to increased thickness and stiffness of the basement membrane (BM) during age-related pathologies and metabolic disorders (e.g. cancer, diabetes, microvasc... Read More about How to study basement membrane stiffness as a biophysical trigger in prostate cancer and other age-related pathologies or metabolic diseases.

Synthesis, structures and cytotoxicity studies of p-sulfonatocalix[4]arene lanthanide complexes (2016)
Journal Article
Miller-Shakesby, D. M., Burke, B. P., Nigam, S., Stasiuk, G. J., Prior, T. J., Archibald, S. J., & Redshaw, C. (2016). Synthesis, structures and cytotoxicity studies of p-sulfonatocalix[4]arene lanthanide complexes. CrystEngComm RSC, 18(26), 4977-4987. https://doi.org/10.1039/c6ce00209a

A number of p-sulfonatocalix[4]arene complexes of the lanthanides (Tb, Gd, and Eu) have been prepared, some in the presence of tetraazamacrocycle 1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid (DO3A), and fully characterised. Crystal structure d... Read More about Synthesis, structures and cytotoxicity studies of p-sulfonatocalix[4]arene lanthanide complexes.

Current advances in ligand design for inorganic positron emission tomography tracers ⁶⁸Ga, ⁶⁴Cu, ⁸⁹Zr and ⁴⁴Sc (2016)
Journal Article
Price, T. W., Greenman, J., & Stasiuk, G. J. (2016). Current advances in ligand design for inorganic positron emission tomography tracers ⁶⁸Ga, ⁶⁴Cu, ⁸⁹Zr and ⁴⁴Sc. Dalton Transactions : an international journal of inorganic chemistry, 45(40), 15702-15724. https://doi.org/10.1039/c5dt04706d

A key part of the development of metal based Positron Emission Tomography probes is the chelation of the radiometal. In this review the recent developments in the chelation of four positron emitting radiometals, 68Ga, 64Cu, 89Zr and 44Sc, are explore... Read More about Current advances in ligand design for inorganic positron emission tomography tracers ⁶⁸Ga, ⁶⁴Cu, ⁸⁹Zr and ⁴⁴Sc.