ATM activation and signaling under hypoxic conditions
(2008)
Journal Article
Bencokova, Z., Kaufmann, M. R., Monteiro dos Santos Pires, I., Lecane, P. S., Giaccia, A. J., & Hammond, E. M. (2009). ATM activation and signaling under hypoxic conditions. Molecular and cellular biology, 29(2), 526-537. https://doi.org/10.1128/MCB.01301-08
The ATM kinase has previously been shown to respond to the DNA damage induced by reoxygenation following hypoxia by initiating a Chk 2-dependent cell cycle arrest in the G2 phase. Here we show that ATM is both phosphorylated and active during exposur... Read More about ATM activation and signaling under hypoxic conditions.