Radiosensitization of renal cell carcinoma in vitro through the induction of autophagy

Ferguson, David J.P.; Anbalagan, Selvakumar; Monteiro dos Santos Pires, Isabel; Blick, Christopher; Hill, Mark A.; Ferguson, David J. P.; Chan, Denise A.; Hammond, Ester M.

doi:10.1016/j.radonc.2012.04.001

All Outputs (2)

Targeting radiation-resistant hypoxic tumour cells through ATR inhibition (2012)
Journal Article
Monteiro dos Santos Pires, I., Olcina, M. M., Anbalagan, S., Pollard, J. R., Reaper, P. M., Charlton, P. A., McKenna, W. G., & Hammond, E. M. (2012). Targeting radiation-resistant hypoxic tumour cells through ATR inhibition. The British Journal of Cancer, 107(2), 291-299. https://doi.org/10.1038/bjc.2012.265

Background:Most solid tumours contain regions of sub-optimal oxygen concentration (hypoxia). Hypoxic cancer cells are more resistant to radiotherapy and represent the most aggressive fraction of a tumour. It is therefore essential that strategies con... Read More about Targeting radiation-resistant hypoxic tumour cells through ATR inhibition.

Radiosensitization of renal cell carcinoma in vitro through the induction of autophagy (2012)
Journal Article
Anbalagan, S., Monteiro dos Santos Pires, I., Blick, C., Hill, M. A., Ferguson, D. J. P., Chan, D. A., & Hammond, E. M. (2012). Radiosensitization of renal cell carcinoma in vitro through the induction of autophagy. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 103(3), 388-393. https://doi.org/10.1016/j.radonc.2012.04.001

Background and purpose: For patients diagnosed with advanced renal cell carcinoma (RCC), there are few therapeutic options. Radiation therapy is predominantly used to treat metastasis and has not proven effective in the adjuvant setting for renal can... Read More about Radiosensitization of renal cell carcinoma in vitro through the induction of autophagy.