All Outputs (4)

The cardiorespiratory and vascular adaptations to a routine UK exercise based cardiac rehabilitation programme (2015)
Thesis
Nichols, S. J. (2015). The cardiorespiratory and vascular adaptations to a routine UK exercise based cardiac rehabilitation programme. (Thesis). University of Hull. Retrieved from https://hull-repository.worktribe.com/output/4218451

Introduction: Recent data suggests that UK cardiac rehabilitation (CR) programmes do not substantially improve cardiorespiratory fitness (CRF) or patient survival. The exercise dose prescribed as part of a routine CR programme may be insufficient. Th... Read More about The cardiorespiratory and vascular adaptations to a routine UK exercise based cardiac rehabilitation programme.

Exploring quality of life in patients with and without heart failure (2015)
Journal Article
Zhang, J., Hobkirk, J., Carroll, S., Pellicori, P., Clark, A. L., & Cleland, J. G. (2016). Exploring quality of life in patients with and without heart failure. International journal of cardiology, 202, 676-684. https://doi.org/10.1016/j.ijcard.2015.09.076

Aims The EuroHeart Failure Survey Questionnaire (EHFSQ-1) has 39 questions on symptoms and quality of life (QoL); many items are related. We sought to identify underlying clusters amongst EHFSQ-1 questions, construct an overall “QoL score” and invest... Read More about Exploring quality of life in patients with and without heart failure.

Development of a human model for the study of effects of hypoxia, exercise, and sildenafil on cardiac and vascular function in chronic heart failure (2015)
Journal Article
Damy, T., Hobkirk, J., Walters, M., Ciobanu, A., Rigby, A. S., Kallvikbacka-Bennett, A., Guellich, A., Dubois-Rande, J.-L., Hittinger, L., Clark, A. L., & Cleland, J. G. F. (2015). Development of a human model for the study of effects of hypoxia, exercise, and sildenafil on cardiac and vascular function in chronic heart failure. Journal of Cardiovascular Pharmacology, 66(3), 229-238. https://doi.org/10.1097/fjc.0000000000000262

Background: Pulmonary hypertension is associated with poor outcome in patients with chronic heart failure (CHF) and may be a therapeutic target. Our aims were to develop a noninvasive model for studying pulmonary vasoreactivity in CHF and characteriz... Read More about Development of a human model for the study of effects of hypoxia, exercise, and sildenafil on cardiac and vascular function in chronic heart failure.

On the functional overlap between complement and anti-microbial peptides (2015)
Journal Article
Stover, C. M., Hobkirk, J., Browning, M. J., Mohamed, F., & Zimmer, J. (2015). On the functional overlap between complement and anti-microbial peptides. Frontiers in immunology, 5(JAN), Article 689. https://doi.org/10.3389/fimmu.2014.00689

Intriguingly, activated complement and anti-microbial peptides share certain functionalities; lytic, phagocytic, and chemo-attractant activities and each may, in addition, exert cell instructive roles. Each has been shown to have distinct LPS detoxif... Read More about On the functional overlap between complement and anti-microbial peptides.