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A new in vitro screening bioassay for the ecotoxicological evaluation of the estrogenic responses of environmental chemicals using roach (Rutilus rutilus) liver explant culture (2010)
Journal Article
Gerbron, M., Geraudie, P., Rotchell, J., & Minier, C. (2010). A new in vitro screening bioassay for the ecotoxicological evaluation of the estrogenic responses of environmental chemicals using roach (Rutilus rutilus) liver explant culture. Environmental Toxicology, 25(5), 510-516. https://doi.org/10.1002/tox.20596

There is growing evidence that many chemicals released in the environment are able to disturb the normal endocrinology of organisms affecting the structure and function of their reproductive system. This has prompted the scientific community to devel... Read More about A new in vitro screening bioassay for the ecotoxicological evaluation of the estrogenic responses of environmental chemicals using roach (Rutilus rutilus) liver explant culture.

Effects of estrogen exposure in mussels, Mytilus edulis, at different stages of gametogenesis (2010)
Journal Article
Ciocan, C. M., Cubero-Leon, E., Puinean, A. M., Hill, E. M., Minier, C., Osada, M., Fenlon, K., & Rotchell, J. M. (2010). Effects of estrogen exposure in mussels, Mytilus edulis, at different stages of gametogenesis. Environmental pollution, 158(9), 2977-2984. https://doi.org/10.1016/j.envpol.2010.05.025

Mytilus edulis were exposed to 17β-estradiol (E2) and the synthetic estrogens ethinyl estradiol (EE2) and estradiol benzoate (EB) for 10 days. Two exposures were performed to determine their effect on vitellogenin (VTG) and estrogen receptor 2 (ER2)... Read More about Effects of estrogen exposure in mussels, Mytilus edulis, at different stages of gametogenesis.

Estrogens disrupt serotonin receptor and cyclooxygenase mRNA expression in the gonads of mussels (Mytilus edulis) (2010)
Journal Article
Cubero-Leon, E., Ciocan, C. M., Hill, E. M., Osada, M., Kishida, M., Itoh, N., Kondo, R., Minier, C., & Rotchell, J. M. (2010). Estrogens disrupt serotonin receptor and cyclooxygenase mRNA expression in the gonads of mussels (Mytilus edulis). Aquatic Toxicology, 98(2), 178-187. https://doi.org/10.1016/j.aquatox.2010.02.007

Estrogenic contaminants in the aquatic environment are associated with feminisation of male fish, however their effects on some invertebrate species, such as bivalve molluscs, have yet to be characterised. Gametogenesis represents a critical step in... Read More about Estrogens disrupt serotonin receptor and cyclooxygenase mRNA expression in the gonads of mussels (Mytilus edulis).