All Outputs (26)

Aetiological investigations in early developmental impairment: Are they worth it? (2017)
Journal Article
Hart, A. R., Sharma, R., Atherton, M., Alabed, S., Simpson, S., Barfield, S., Cohen, J., McGlashan, N., Ravi, A., Parker, M. J., & Connolly, D. J. (2017). Aetiological investigations in early developmental impairment: Are they worth it?. Archives of Disease in Childhood, 102(11), 1004-1013. https://doi.org/10.1136/archdischild-2017-312843

Objective To study the frequency a diagnosis is made in children with early developmental impairment (EDI), and the contribution made to diagnosis by specific investigations.

Design Retrospective case note review.

Setting Community, neurodisability... Read More about Aetiological investigations in early developmental impairment: Are they worth it?.

Does early intervention improve outcomes in physiotherapy management of lumbar radicular syndrome? A mixed-methods study protocol (2017)
Journal Article
Reddington, M., Walters, S. J., Cohen, J., & Baxter, S. (2017). Does early intervention improve outcomes in physiotherapy management of lumbar radicular syndrome? A mixed-methods study protocol. BMJ open, 7(3), Article e014422. https://doi.org/10.1136/bmjopen-2016-014422

© Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-And-licensing/. Introduction Lumbar radicular syndrome (LRS) can be a... Read More about Does early intervention improve outcomes in physiotherapy management of lumbar radicular syndrome? A mixed-methods study protocol.

A systematic review and meta-analysis to determine the contribution of mr imaging to the diagnosis of foetal brain abnormalities In Utero (2016)
Journal Article
Jarvis, D., Mooney, C., Cohen, J., Papaioannou, D., Bradburn, M., Sutton, A., & Griffiths, P. D. (2017). A systematic review and meta-analysis to determine the contribution of mr imaging to the diagnosis of foetal brain abnormalities In Utero. European Radiology, 27(6), 2367-2380. https://doi.org/10.1007/s00330-016-4563-4

© 2016, The Author(s). Objectives: This systematic review was undertaken to define the diagnostic performance of in utero MR (iuMR) imaging when attempting to confirm, exclude or provide additional information compared with the information provided b... Read More about A systematic review and meta-analysis to determine the contribution of mr imaging to the diagnosis of foetal brain abnormalities In Utero.

DiPALS: Diaphragm pacing in patients with amyotrophic lateral sclerosis – A randomised controlled trial (2016)
Journal Article
McDermott, C. J., Bradburn, M. J., Maguire, C., Cooper, C. L., Baird, W. O., Baxter, S. K., Cohen, J., Cantrill, H., Dixon, S., Ackroyd, R., Baudouin, S., Bentley, A., Berrisford, R., Bianchi, S., Bourke, S. C., Darlison, R., Ealing, J., Elliott, M., Fitzgerald, P., Galloway, S., …Shaw, P. J. (2016). DiPALS: Diaphragm pacing in patients with amyotrophic lateral sclerosis – A randomised controlled trial. Health Technology Assessment, 20(45), 1-218. https://doi.org/10.3310/hta20450

Background
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease resulting in death, usually from respiratory failure, within 2–3 years of symptom onset. Non-invasive ventilation (NIV) is a treatment that when given to patients in respir... Read More about DiPALS: Diaphragm pacing in patients with amyotrophic lateral sclerosis – A randomised controlled trial.

The 3Mg trial: a randomised controlled trial of intravenous or nebulised magnesium sulphate versus placebo in adults with acute severe asthma (2014)
Journal Article
Goodacre, S., Cohen, J., Bradburn, M., Stevens, J., Gray, A., Benger, J., & Coats, T. (in press). The 3Mg trial: a randomised controlled trial of intravenous or nebulised magnesium sulphate versus placebo in adults with acute severe asthma. Health Technology Assessment, 18(22), 1-167. https://doi.org/10.3310/hta18220

Background: Magnesium sulphate, administered by the intravenous (i.v.) or inhaled (nebulised) route, has been proposed as a treatment for adults with acute severe asthma. Existing trials show mixed results and uncertain evidence of benefit. Objective... Read More about The 3Mg trial: a randomised controlled trial of intravenous or nebulised magnesium sulphate versus placebo in adults with acute severe asthma.

Intravenous or nebulised magnesium sulphate versus standard therapy for severe acute asthma (3Mg trial): a double-blind, randomised controlled trial (2013)
Journal Article
Goodacre, S., Cohen, J., Bradburn, M., Gray, A., Benger, J., & Coats, T. (2013). Intravenous or nebulised magnesium sulphate versus standard therapy for severe acute asthma (3Mg trial): a double-blind, randomised controlled trial. The lancet. Respiratory medicine, 1(4), 293-300. https://doi.org/10.1016/S2213-2600%2813%2970070-5

Background: Previous studies suggested intravenous or nebulised magnesium sulphate (MgSO4) might improve respiratory function in patients with acute asthma. We aimed to determine whether intravenous or nebulised MgSO4 improve symptoms of breathlessne... Read More about Intravenous or nebulised magnesium sulphate versus standard therapy for severe acute asthma (3Mg trial): a double-blind, randomised controlled trial.