Alterations in platelet alpha-granule secretion and adhesion on collagen under flow in mice lacking the atypical rho GTPase RhoBTB3
(2019)
Journal Article
Berger, M., Riley, D. R. J., Lutz, J., Khalil, J. S., Aburima, A., Naseem, K. M., & Rivero, F. (2019). Alterations in platelet alpha-granule secretion and adhesion on collagen under flow in mice lacking the atypical rho GTPase RhoBTB3. Cells, 8(2), Article 149. https://doi.org/10.3390/cells8020149
Typical Rho GTPases, such as Rac1, Cdc42, and RhoA, act as molecular switches regulating various aspects of platelet cytoskeleton reorganization. The loss of these enzymes results in reduced platelet functionality. Atypical Rho GTPases of the RhoBTB... Read More about Alterations in platelet alpha-granule secretion and adhesion on collagen under flow in mice lacking the atypical rho GTPase RhoBTB3.