All Outputs (2)

Next-generation sequencing reveals broad down-regulation of microRNAs in secondary progressive multiple sclerosis CD4+ T cells (2016)
Journal Article
Sanders, K. A., Benton, M. C., Lea, R. A., Maltby, V. E., Agland, S., Griffin, N., …Lechner-Scott, J. (2016). Next-generation sequencing reveals broad down-regulation of microRNAs in secondary progressive multiple sclerosis CD4+ T cells. Clinical epigenetics, 8(1), Article 87. https://doi.org/10.1186/s13148-016-0253-y

Background: Immunoactivation is less evident in secondary progressive MS (SPMS) compared to relapsing-remitting disease. MicroRNA (miRNA) expression is integral to the regulation of gene expression; determining their impact on immune-related cell fun... Read More about Next-generation sequencing reveals broad down-regulation of microRNAs in secondary progressive multiple sclerosis CD4+ T cells.

Erythrocytes in multiple sclerosis – forgotten contributors to the pathophysiology? (2016)
Journal Article
Groen, K., Maltby, V. E., Sanders, K. A., Scott, R. J., Tajouri, L., & Lechner-Scott, J. (2016). Erythrocytes in multiple sclerosis – forgotten contributors to the pathophysiology?. Multiple Sclerosis Journal - Experimental, Translational and Clinical, 2, https://doi.org/10.1177/2055217316649981

Multiple sclerosis (MS) is an autoimmune disease characterised by lymphocytic infiltration of the central nervous system and subsequent destruction of myelin and axons. On the background of a genetic predisposition to autoimmunity, environmental trig... Read More about Erythrocytes in multiple sclerosis – forgotten contributors to the pathophysiology?.