All Outputs (3)

Prostacyclin reverses platelet stress fibre formation causing platelet aggregate instability (2017)
Journal Article
Yusuf, M. Z., Raslan, Z., Atkinson, L., Aburima, A., Thomas, S. G., Naseem, K. M., & Calaminus, S. D. (2017). Prostacyclin reverses platelet stress fibre formation causing platelet aggregate instability. Scientific reports, 7(1), Article ARTN 5582. https://doi.org/10.1038/s41598-017-05817-9

Prostacyclin (PGI2) modulates platelet activation to regulate haemostasis. Evidence has emerged to suggest that thrombi are dynamic structures with distinct areas of differing platelet activation. It was hypothesised that PGI2 could reverse platelet... Read More about Prostacyclin reverses platelet stress fibre formation causing platelet aggregate instability.

Energy metabolism of platelets (2017)
Thesis
Aibibula, M. (2017). Energy metabolism of platelets. (Thesis). Hull York Medical School, the University of Hull and the University of York. Retrieved from https://hull-repository.worktribe.com/output/4221806

Undesired platelet activation is associated with a number of diseases characterised by metabolic imbalance, such as hyperlipidaemia. Changes in platelet energy metabolism associated with disease states are unclear. This thesis presents a detailed inv... Read More about Energy metabolism of platelets.

Association of type 1 inositol 1,4,5-trisphosphate receptor (IP₃R1) with protein kinase A and A-kinase Anchoring Protein 9 (AKAP9) in platelets (2017)
Thesis
Trivedi, A. N. (2017). Association of type 1 inositol 1,4,5-trisphosphate receptor (IP₃R1) with protein kinase A and A-kinase Anchoring Protein 9 (AKAP9) in platelets. (Thesis). Hull York Medical School, the University of Hull and the University of York. Retrieved from https://hull-repository.worktribe.com/output/4219204

Cyclic adenosine monophsphoate (cAMP) signalling is thought to regulate inositol-1,4,5 trisphosphate (IP₃)-mediated calcium (Ca²⁺) mobilisation in platelets through protein kinase A (PKA)-mediated phosphorylation, leading to inhibition of inositol-1,... Read More about Association of type 1 inositol 1,4,5-trisphosphate receptor (IP₃R1) with protein kinase A and A-kinase Anchoring Protein 9 (AKAP9) in platelets.