All Outputs (2)

Investigating the effects of arginine methylation inhibitors on microdissected brain tumour biopsies maintained in a miniaturised perfusion system (2023)
Journal Article
Barry, A., Samuel, S. F., Hosni, I., Moursi, A., Feugere, L., Sennett, C. J., …Beltran-Alvarez, P. (2023). Investigating the effects of arginine methylation inhibitors on microdissected brain tumour biopsies maintained in a miniaturised perfusion system. Lab on a chip, 23(11), 2664-2682. https://doi.org/10.1039/d3lc00204g

Arginine methylation is a post-translational modification that consists of the transfer of one or two methyl (CH3) groups to arginine residues in proteins. Several types of arginine methylation occur, namely monomethylation, symmetric dimethylation a... Read More about Investigating the effects of arginine methylation inhibitors on microdissected brain tumour biopsies maintained in a miniaturised perfusion system.

Heat induces multiomic and phenotypic stress propagation in zebrafish embryos (2023)
Journal Article
Feugere, L., Bates, A., Emagbetere, T., Chapman, E., Malcolm, L., Bulmer, K., …Wollenberg Valero, K. C. (2023). Heat induces multiomic and phenotypic stress propagation in zebrafish embryos. PNAS Nexus, 2(5), Article pgad137. https://doi.org/10.1093/pnasnexus/pgad137

Heat alters biology from molecular to ecological levels, but may also have unknown indirect effects. This includes the concept that animals exposed to abiotic stress can induce stress in naive receivers. Here, we provide a comprehensive picture of th... Read More about Heat induces multiomic and phenotypic stress propagation in zebrafish embryos.