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Insufficient exercise intensity for clinical benefit? Monitoring and quantification of a community-based Phase III cardiac rehabilitation programme: A United Kingdom perspective (2019)
Journal Article
Khushhal, A., Nichols, S., Carroll, S., Abt, G., & Ingle, L. (in press). Insufficient exercise intensity for clinical benefit? Monitoring and quantification of a community-based Phase III cardiac rehabilitation programme: A United Kingdom perspective. PloS one, 14(6), https://doi.org/10.1371/journal.pone.0217654

Abstract: Background: In recent years, criticism of the percentage range approach for individualised exercise prescription has intensified and we were concerned that sub-optimal exercise dose (especially intensity) may be in part responsible for the... Read More

Influence of appendicular skeletal muscle mass on resting metabolic equivalents in patients with cardiovascular disease: Implications for exercise training and prescription (2019)
Journal Article
Nichols, S., O'Doherty, A., Carroll, S., & Ingle, L. (in press). Influence of appendicular skeletal muscle mass on resting metabolic equivalents in patients with cardiovascular disease: Implications for exercise training and prescription. European Journal of Preventive Cardiology, https://doi.org/10.1177/2047487319856432

Cardiorespiratory fitness as a predictor of short‐term and lifetime estimated cardiovascular disease risk (2019)
Journal Article
Swainson, M. G., Ingle, L., & Carroll, S. (in press). Cardiorespiratory fitness as a predictor of short‐term and lifetime estimated cardiovascular disease risk. Scandinavian Journal of Medicine and Science in Sports, https://doi.org/10.1111/sms.13468

Development of cardiovascular disease (CVD) remains a public health concern for young-to-middle-aged adults, now exacerbated by the increasing prevalence of obesity and sedentary lifestyles. Cardiorespiratory fitness (CRF) improves the reclassificati... Read More

Does exercise prescription based on estimated heart rate training zones exceed the ventilatory anaerobic threshold in patients with coronary heart disease undergoing usual-care cardiovascular rehabilitation? : a United Kingdom perspective (2019)
Journal Article
Pymer, S., Nichols, S., Prosser, J., Birkett, S., Carroll, S., & Ingle, L. (in press). Does exercise prescription based on estimated heart rate training zones exceed the ventilatory anaerobic threshold in patients with coronary heart disease undergoing usual-care cardiovascular rehabilitation? : a United Kingdom perspective. European Journal of Preventive Cardiology, https://doi.org/10.1177/2047487319852711

Background: In the United Kingdom (UK), exercise intensity is prescribed from a fixed percentage range (% heart rate reserve; %HRR) in cardiac rehabilitation (CR) programmes. We aimed to determine the accuracy of this approach by comparing it with an... Read More

The effects of low-volume high-intensity interval training and circuit training on maximal oxygen uptake (2019)
Journal Article
Birkett, S. T., Nichols, S., Sawrey, R., Gleadall-Siddall, D., McGregor, G., & Ingle, L. (in press). The effects of low-volume high-intensity interval training and circuit training on maximal oxygen uptake. Sport Sciences for Health, https://doi.org/10.1007/s11332-019-00552-2

Purpose: High intensity interval training (HIIT) and circuit training (CT) are popular methods of exercise, eliciting improvements in cardiorespiratory fitness (CRF). However direct comparisons of these two training methods are limited. We investigat... Read More

Home-based exercise programmes for individuals with intermittent claudication: A protocol for an updated systematic review and meta-analysis (2018)
Journal Article
Pymer, S., Tew, G. A., Palmer, J., Ingle, L., Smith, G. E., Chetter, I., & Harwood, A. E. (2018). Home-based exercise programmes for individuals with intermittent claudication: A protocol for an updated systematic review and meta-analysis. SAGE Open Medicine, 6, 205031211881829. doi:10.1177/2050312118818295

Background: The aim of this updated review is to consider the evidence base for the effectiveness of home-based exercise programmes (HEP) as a treatment option for improving walking distance in patients with IC. Methods: The Medline, EMBASE, CINAHL,... Read More

Low skeletal muscle mass is associated with low aerobic capacity and increased mortality risk in patients with coronary heart disease - a CARE CR study (2018)
Journal Article
Nichols, S., O'Doherty, A. F., Taylor, C., Clark, A. L., Carroll, S., & Ingle, L. (2019). Low skeletal muscle mass is associated with low aerobic capacity and increased mortality risk in patients with coronary heart disease - a CARE CR study. Clinical physiology and functional imaging, 39(1), 93-102. https://doi.org/10.1111/cpf.12539

BACKGROUND In patients with chronic heart failure, there is a positive linear relationship between skeletal muscle mass (SMM) and peak oxygen consumption (V˙O2peak ); an independent predictor of all-cause mortality. We investigated the association b... Read More

The BASES expert statement on exercise training for people with intermittent claudication due to peripheral arterial disease (2018)
Report
Tew, G., Harwood, A., Ingle, L., Chetter, I., & Doherty, P. (2018). The BASES expert statement on exercise training for people with intermittent claudication due to peripheral arterial disease. British Association of Sports & Exercise Science

Lower-limb peripheral arterial disease (PAD) is a type of cardiovascular disease in which the blood vessels (arteries) that carry blood to the legs and feet are hardened and narrowed or blocked by the build-up of fatty plaques (called atheroma). It a... Read More

Is cardiorespiratory fitness related to cardiometabolic health and all-cause mortality risk in patients with coronary heart disease? A CARE CR study (2018)
Journal Article
Nichols, S., Taylor, C., Page, R., Kallvikbacka-Bennett, A., Nation, F., Goodman, T., …Ingle, L. (2018). Is cardiorespiratory fitness related to cardiometabolic health and all-cause mortality risk in patients with coronary heart disease? A CARE CR study. Sports Medicine - Open, 4(1), https://doi.org/10.1186/s40798-018-0138-z

Background: Higher cardiorespiratory fitness (CRF) is associated with lower morbidity and mortality in patients with coronary heart disease (CHD). The mechanisms for this are not fully understood. A more favourable cardiometabolic risk factor profi... Read More

CARE CR-Cardiovascular and cardiorespiratory Adaptations to Routine Exercise-based Cardiac Rehabilitation: a study protocol for a community-based controlled study with criterion methods (2018)
Journal Article
Nichols, S., Nation, F., Goodman, T., Clark, A. L., Carroll, S., & Ingle, L. (2018). CARE CR-Cardiovascular and cardiorespiratory Adaptations to Routine Exercise-based Cardiac Rehabilitation: a study protocol for a community-based controlled study with criterion methods. BMJ open, 8(1), e019216. https://doi.org/10.1136/bmjopen-2017-019216

Introduction Cardiac rehabilitation (CR) reduces all-cause and cardiovascular mortality in patients with coronary heart disease (CHD). Much of this improvement has been attributed to the beneficial effects of structured exercise training. However, UK... Read More

The effects of acute interval exercise and strawberry intake on postprandial lipemia (2017)
Journal Article
O’Doherty, A., Jones, H. S., Sathyapalan, T., Ingle, L., & Carroll, S. (2017). The effects of acute interval exercise and strawberry intake on postprandial lipemia. Medicine and Science in Sports and Exercise, 49(11), 2315-2323. https://doi.org/10.1249/MSS.0000000000001341

Purpose: Raised postprandial triglycerides (TAG) and related oxidative stresses are strongly associated with increased cardiovascular disease (CVD) risk. Acute exercise and strawberry ingestion independently ameliorate postprandial lipid excursions a... Read More

Estimated peak functional capacity: an accurate method for assessing change in peak oxygen consumption after cardiac rehabilitation? (2017)
Journal Article
Nichols, S., Gleadall-Siddall, D. O., Antony, R., Clark, A. L., Cleland, J. G. F., Carroll, S., & Ingle, L. (2018). Estimated peak functional capacity: an accurate method for assessing change in peak oxygen consumption after cardiac rehabilitation?. Clinical physiology and functional imaging, 38(4), 681-688. https://doi.org/10.1111/cpf.12468

Summary Objective Cardiopulmonary exercise testing (CPET) is the ‘gold standard’ method of determining VO2peak. When CPET is unavailable, VO2peak may be estimated from treadmill or cycle ergometer workloads and expressed as estimated metabolic equiva... Read More

A randomized controlled trial to establish the impact of aquatic exercise training on functional capacity, balance, and perceptions of fatigue in female patients with multiple sclerosis (2017)
Journal Article
Kargarfard, M., Shariat, A., Ingle, L., Cleland, J. A., & Kargarfard, M. (2018). A randomized controlled trial to establish the impact of aquatic exercise training on functional capacity, balance, and perceptions of fatigue in female patients with multiple sclerosis. Archives of physical medicine and rehabilitation, 99(2), 234-241. https://doi.org/10.1016/j.apmr.2017.06.015

Objective: To assess the effects of 8-weeks aquatic exercise training on functional capacity, balance, and perceptions of fatigue in women with multiple sclerosis (MS). Design: A randomized controlled design. Setting: Referral center of a multiple sc... Read More

Exercise dose and all-cause mortality within extended cardiac rehabilitation: a cohort study (2017)
Journal Article
Taylor, C., Tsakirides, C., Moxon, J., Moxon, J. W., Dudfield, M., Witte, K., …Carroll, S. (2017). Exercise dose and all-cause mortality within extended cardiac rehabilitation: a cohort study. Open heart, 4(2), e000623. https://doi.org/10.1136/openhrt-2017-000623

Aims: To investigate the relationship between exercise participation, exercise ‘dose’ expressed as metabolic equivalent (MET) hours (h) per week, and prognosis in individuals attending an extended, community-based exercise rehabilitation programme. M... Read More

Validity and reliability of the Apple Watch for measuring heart rate during exercise (2017)
Journal Article
Khushhal, A., Nichols, S., Evans, W., Gleadall-Siddall, D., Page, R., O'Doherty, A. F., …Abt, G. (2017). Validity and reliability of the Apple Watch for measuring heart rate during exercise. SMIO / Sports Medicine International Open, 1(6), E206-E211. https://doi.org/10.1055/s-0043-120195

We examined the validity and reliability of the Apple Watch heart rate sensor during and in recovery from exercise. Twenty-one males completed treadmill exercise while wearing two Apple Watches (left and right wrists) and a Polar S810i monitor (crite... Read More

Validity of telemetric-derived measures of heart rate variability: a systematic review (2016)
Journal Article
Board, E., Ispoglou, T., & Ingle, L. (2016). Validity of telemetric-derived measures of heart rate variability: a systematic review. Journal of exercise physiology online / American Society of Exercise Physiologists, 19(6), 64-84

Heart rate variability (HRV) is a widely accepted indirect measure of autonomic function with widespread application across many settings. Although traditionally measured from the ‘gold standard’ criterion electrocardiography (ECG), the development o... Read More

Characterization of the metabolically healthy phenotype in overweight and obese British men (2016)
Journal Article
Ingle, L., Swainson, M., Brodie, D., & Sandercock, G. R. (2017). Characterization of the metabolically healthy phenotype in overweight and obese British men. Preventive Medicine, 94, 7-11. https://doi.org/10.1016/j.ypmed.2016.11.001

We calculated the prevalence of the metabolically healthy but obese (MHO) phenotype in (n=9 177) British men (age 48.9±7.4 years) attending preventive health screening between 2000 and 2009. We examined differences in cardiorespiratory fitness (Fitne... Read More

High-intensity interval training versus moderate-intensity steady-state training in UK cardiac rehabilitation programmes (HIIT or MISS UK): study protocol for a multicentre randomised controlled trial and economic evaluation (2016)
Journal Article
McGregor, G., Nichols, S., Hamborg, T., Bryning, L., Tudor-Edwards, R., Markland, D., …Backx, K. (2016). High-intensity interval training versus moderate-intensity steady-state training in UK cardiac rehabilitation programmes (HIIT or MISS UK): study protocol for a multicentre randomised controlled trial and economic evaluation. BMJ open, 6(11), e012843. https://doi.org/10.1136/bmjopen-2016-012843

Introduction: Current international guidelines for cardiac rehabilitation (CR) advocate moderate-intensity exercise training (MISS, moderate-intensity steady state). This recommendation predates significant advances in medical therapy for coronary he... Read More

Associations between cardiorespiratory fitness and the metabolic syndrome in British men (2016)
Journal Article
Ingle, L., Mellis, M., Brodie, D., & Sandercock, G. R. (2017). Associations between cardiorespiratory fitness and the metabolic syndrome in British men. Heart, 103(7), 524-528. https://doi.org/10.1136/heartjnl-2016-310142

Background: Age and body mass index (BMI) are positively associated with the development of the metabolic syndrome (MetS). Cardiorespiratory fitness (CRF) can attenuate BMI-related increases in prevalence of MetS, but the nature of this association a... Read More

The repeatability of the abbreviated (4-h) Oral Fat Tolerance Test and influence of prior acute aerobic exercise (2016)
Journal Article
O’Doherty, A. F., Sathyapalan, T., Rigby, A. S., Ingle, L., & Carroll, S. (2018). The repeatability of the abbreviated (4-h) Oral Fat Tolerance Test and influence of prior acute aerobic exercise. European Journal of Nutrition, 57(1), 309-318. https://doi.org/10.1007/s00394-016-1320-z

© 2016 The Author(s) Purpose: The Oral Fat Tolerance Test (OFTT) is regarded as a repeatable measure used to assess postprandial triglyceride (TAG) levels, with higher levels observed in cardio-metabolic disorders. Acute aerobic exercise intervention... Read More