All Outputs (48)

How accurate is the current picture of human genetic variation? (2008)
Journal Article
Romero, I. G., Manica, A., Goudet, J., Handley, L. L., & Balloux, F. (2009). How accurate is the current picture of human genetic variation?. Heredity, 102(2), 120-126. https://doi.org/10.1038/hdy.2008.89

Our understanding of the distribution of worldwide human genomic diversity has greatly increased over recent years thanks to the availability of large data sets derived from short tandem repeats (STRs), insertion deletion polymorphisms (indels) and s... Read More about How accurate is the current picture of human genetic variation?.

Genetic structure of European sheep breeds. (2007)
Journal Article
Lawson Handley, L. J., Byrne, K., Santucci, F., Townsend, S., Taylor, M., Bruford, M. W., & Hewitt, G. M. (2007). Genetic structure of European sheep breeds. Heredity, 99(6), 620-631. https://doi.org/10.1038/sj.hdy.6801039

Large-scale evaluations of genetic diversity in domestic livestock populations are necessary so that region-specific conservation measures can be implemented. We performed the first such survey in European sheep by analysing 820 individuals from 29 g... Read More about Genetic structure of European sheep breeds..

Going the distance: human population genetics in a clinal world (2007)
Journal Article
Lawson Handley, L. J., Manica, A., Goudet, J., & Balloux, F. (2007). Going the distance: human population genetics in a clinal world. Trends in Genetics, 23(9), 432-439. https://doi.org/10.1016/j.tig.2007.07.002

Global human genetic variation is greatly influenced by geography, with genetic differentiation between populations increasing with geographic distance and within-population diversity decreasing with distance from Africa. In fact, these ’clines’ can... Read More about Going the distance: human population genetics in a clinal world.

Advances in our understanding of mammalian sex-biased dispersal (2007)
Journal Article
Lawson Handley, L., & Perrin, N. (2007). Advances in our understanding of mammalian sex-biased dispersal. Molecular ecology, 16(8), 1559-1578. https://doi.org/10.1111/j.1365-294X.2006.03152.x

Sex-biased dispersal is an almost ubiquitous feature of mammalian life history, but the evolutionary causes behind these patterns still require much clarification. A quarter of a century since the publication of seminal papers describing general patt... Read More about Advances in our understanding of mammalian sex-biased dispersal.

Is urbanization scrambling the genetic structure of human populations? A case study (2006)
Journal Article
Ashrafian-Bonab, M., Lawson Handley, L. J., & Balloux, F. (2007). Is urbanization scrambling the genetic structure of human populations? A case study. Heredity, 98(3), 151-156. https://doi.org/10.1038/sj.hdy.6800918

Recent population expansion and increased migration linked to urbanization are assumed to be eroding the genetic structure of human populations. We investigated change in population structure over three generations by analysing both demographic and m... Read More about Is urbanization scrambling the genetic structure of human populations? A case study.

Low Y chromosome variation in Saudi-Arabian hamadryas baboons (Papio hamadryas hamadryas) (2006)
Journal Article
Lawson Handley, L. J., Hammond, R. L., Emaresi, G., Reber, A., & Perrin, N. (2006). Low Y chromosome variation in Saudi-Arabian hamadryas baboons (Papio hamadryas hamadryas). Heredity, 96(4), 298-303. https://doi.org/10.1038/sj.hdy.6800803

It is important to characterise the amount of variation on the mammalian Y chromosome in order to assess its potential for use in evolutionary studies. We report very low levels of polymorphism on the Y chromosome of Saudi-Arabian hamadryas baboons,... Read More about Low Y chromosome variation in Saudi-Arabian hamadryas baboons (Papio hamadryas hamadryas).

Genetic evidence for female-biased dispersal and gene flow in a polygynous primate (2006)
Journal Article
Hammond, R. L., Handley, L. J. L., Winney, B. J., Bruford, M. W., & Perrin, N. (2006). Genetic evidence for female-biased dispersal and gene flow in a polygynous primate. Proceedings of the Royal Society B: Biological Sciences, 273(1585), 479-484. https://doi.org/10.1098/rspb.2005.3257

Many models of sex-biased dispersal predict that the direction of sex-bias depends upon a species' mating system. In agreement with this, almost all polygynous mammals show male-biased dispersal whereas largely monogamous birds show female-biased dis... Read More about Genetic evidence for female-biased dispersal and gene flow in a polygynous primate.

Evolutionary history of the greater white-toothed shrew (Crocidura russula) inferred from analysis of mtDNA, Y, and X chromosome markers (2005)
Journal Article
Brändli, L., Handley, L.-J. L., Vogel, P., & Perrin, N. (2005). Evolutionary history of the greater white-toothed shrew (Crocidura russula) inferred from analysis of mtDNA, Y, and X chromosome markers. Molecular Phylogenetics and Evolution, 37(3), 832-844. https://doi.org/10.1016/j.ympev.2005.06.019

We investigate the evolutionary history of the greater white-toothed shrew across its distribution in northern Africa and mainland Europe using sex-specific (mtDNA and Y chromosome) and biparental (X chromosome) markers. All three loci confirm a larg... Read More about Evolutionary history of the greater white-toothed shrew (Crocidura russula) inferred from analysis of mtDNA, Y, and X chromosome markers.