Transport cycle intermediate in small multidrug resistance protein is revealed by substrate fluorescence
(2007)
Journal Article
Basting, D., Lorch, M., Lehner, I., & Glaubitz, C. (2008). Transport cycle intermediate in small multidrug resistance protein is revealed by substrate fluorescence. FASEB Journal, 22(2), 365-373. https://doi.org/10.1096/fj.07-9162com
Efflux pumps of the small multidrug resistance family bind cationic, lipophilic antibiotics and transport them across the membrane in exchange for protons. The transport cycle must involve various conformational states of the protein needed for subst... Read More about Transport cycle intermediate in small multidrug resistance protein is revealed by substrate fluorescence.