All Outputs (22)

KDM4B is a master regulator of the estrogen receptor signalling cascade (2013)
Journal Article
Gaughan, L., Stockley, J., Coffey, K., O’Neill, D., Jones, D. L., Wade, M., Wright, J., Moore, M., Tse, S., Rogerson, L., & Robson, C. N. (2013). KDM4B is a master regulator of the estrogen receptor signalling cascade. Nucleic Acids Research, 41(14), 6892-6904. https://doi.org/10.1093/nar/gkt469

The importance of the estrogen receptor (ER) in breast cancer (BCa) development makes it a prominent target for therapy. Current treatments, however, have limited effectiveness, and hence the definition of new therapeutic targets is vital. The ER is... Read More about KDM4B is a master regulator of the estrogen receptor signalling cascade.

Post-transcriptional exon shuffling events in humans can be evolutionarily conserved and abundant (2011)
Journal Article
Al-Balool, H. H., Weber, D., Liu, Y., Wade, M., Guleria, K., Nam, P. L. P., Clayton, J., Rowe, W., Coxhead, J., Irving, J., Elliott, D. J., Hall, A. G., Santibanez-Koref, M., & Jackson, M. S. (2011). Post-transcriptional exon shuffling events in humans can be evolutionarily conserved and abundant. Genome research, 21(11), 1788-1799. https://doi.org/10.1101/gr.116442.110

In silico analyses have established that transcripts from some genes can be processed into RNAs with rearranged exon order relative to genomic structure (post-transcriptional exon shuffling, or PTES). Although known to contribute to transcriptome div... Read More about Post-transcriptional exon shuffling events in humans can be evolutionarily conserved and abundant.