Phase II, double blind, placebo controlled, multi-site study to evaluate the safety, feasibility and desirability of conducting a phase III study of anamorelin for anorexia in people with small cell lung cancer: A study protocol (LUANA trial)

Sousa, Mariana S.; Martin, Peter; Johnson, Miriam J.; Lind, Michael; Maddocks, Matthew; Bullock, Alex; Agar, Meera; Chang, Sungwon; Kochovska, Slavica; Kinchin, Irina; Morgan, Deidre; Fazekas, Belinda; Razmovski-Naumovski, Valentina; Lee, Jessica T; Itchins, Malinda; Bray, Victoria; Currow, David C

doi:10.1371/journal.pone.0285850

All Outputs (2)

Geriatric assessment prior to cancer treatment: a health economic evaluation   (2023)
Journal Article
Johnson, M. J., McKenzie, G. A. G., Lind, M. J., Kelly, C., & Parrott, S. (2023). Geriatric assessment prior to cancer treatment: a health economic evaluation  . Journal of Geriatric Oncology, 14(6), Article 101504. https://doi.org/10.1016/j.jgo.2023.101504

Introduction: To address uncertainty regarding the cost-effectiveness of implementing geriatric assessment (GA) in oncology practice, we undertook a synthetic, model-based economic evaluation. Materials and Methods: A decision-analytic model with emb... Read More about Geriatric assessment prior to cancer treatment: a health economic evaluation  .

Phase II, double blind, placebo controlled, multi-site study to evaluate the safety, feasibility and desirability of conducting a phase III study of anamorelin for anorexia in people with small cell lung cancer: A study protocol (LUANA trial) (2023)
Journal Article
Sousa, M. S., Martin, P., Johnson, M. J., Lind, M., Maddocks, M., Bullock, A., Agar, M., Chang, S., Kochovska, S., Kinchin, I., Morgan, D., Fazekas, B., Razmovski-Naumovski, V., Lee, J. T., Itchins, M., Bray, V., & Currow, D. C. (2023). Phase II, double blind, placebo controlled, multi-site study to evaluate the safety, feasibility and desirability of conducting a phase III study of anamorelin for anorexia in people with small cell lung cancer: A study protocol (LUANA trial). PLoS ONE, 18(5 May), Article e0285850. https://doi.org/10.1371/journal.pone.0285850

Anorexia is experienced by most people with lung cancer during the course of their disease and treatment. Anorexia reduces response to chemotherapy and the ability of patients to cope with, and complete their treatment leading to greater morbidity, p... Read More about Phase II, double blind, placebo controlled, multi-site study to evaluate the safety, feasibility and desirability of conducting a phase III study of anamorelin for anorexia in people with small cell lung cancer: A study protocol (LUANA trial).