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All Outputs (207)

In silico (computed) modelling of doses and dosing regimens associated with morphine levels above international legal driving limits (2018)
Journal Article
Boland, J. W., Johnson, M., Ferreira, D., & Berry, D. J. (2018). In silico (computed) modelling of doses and dosing regimens associated with morphine levels above international legal driving limits. Palliative medicine, 32(7), 1222-1232. https://doi.org/10.1177/0269216318773956

Background: Morphine can cause central nervous system side effects which impair driving skills. The legal blood morphine concentration limit for driving is 20 µg/L in France/Poland/Netherlands and 80 µg/L in England/Wales. There is no guidance as to... Read More about In silico (computed) modelling of doses and dosing regimens associated with morphine levels above international legal driving limits.

The feasibility of a randomised controlled trial to compare the cost-effectiveness of palliative cardiology or usual care in people with advanced heart failure: Two exploratory prospective cohorts (2018)
Journal Article
Johnson, M. J., McSkimming, P., McConnachie, A., Geue, C., Millerick, Y., Briggs, A., & Hogg, K. (2018). The feasibility of a randomised controlled trial to compare the cost-effectiveness of palliative cardiology or usual care in people with advanced heart failure: Two exploratory prospective cohorts. Palliative medicine, 32(6), 1133-1141. https://doi.org/10.1177/0269216318763225

© 2018, © The Author(s) 2018. Background: The effectiveness of cardiology-led palliative care is unknown; we have insufficient information to conduct a full trial. Aim: To assess the feasibility (recruitment/retention, data quality, variability/sampl... Read More about The feasibility of a randomised controlled trial to compare the cost-effectiveness of palliative cardiology or usual care in people with advanced heart failure: Two exploratory prospective cohorts.

Cancer patients’ experiences of living with venous thromboembolism: A systematic review and qualitative thematic synthesis (2018)
Journal Article
Benelhaj, N. B., Hutchinson, A., Maraveyas, A. M., Seymour, J. D., Ilyas, M. W., & Johnson, M. J. (2018). Cancer patients’ experiences of living with venous thromboembolism: A systematic review and qualitative thematic synthesis. Palliative medicine, 32(5), 1010-1020. https://doi.org/10.1177/0269216318757133

Background: Cancer-Associated thrombosis is common. Recommended treatment is daily injected low-molecular-weight heparin for 6months. Most studies focus on prophylaxis and treatment; few have explored patients’ experience. Aims To identify and sy... Read More about Cancer patients’ experiences of living with venous thromboembolism: A systematic review and qualitative thematic synthesis.

Palliative care specialists' perceptions concerning referral of haematology patients to their services: Findings from a qualitative study (2018)
Journal Article
McCaughan, D., Roman, E., Smith, A. G., Garry, A. C., Johnson, M. J., Patmore, R. D., Howard, M. R., & Howell, D. A. (2018). Palliative care specialists' perceptions concerning referral of haematology patients to their services: Findings from a qualitative study. BMC Palliative Care, 17(1), Article 33. https://doi.org/10.1186/s12904-018-0289-1

Background Haematological malignancies (leukaemias, lymphomas and myeloma) are complex cancers that are relatively common, affect all ages and have divergent outcomes. Although the symptom burden of these diseases is comparable to other cancers, pati... Read More about Palliative care specialists' perceptions concerning referral of haematology patients to their services: Findings from a qualitative study.

Living with breathlessness: a systematic literature review and qualitative synthesis (2018)
Journal Article
Hutchinson, A., Barclay-Klingle, N., Galvin, K., & Johnson, M. J. (2018). Living with breathlessness: a systematic literature review and qualitative synthesis. European respiratory journal, 51(2), 1701477. https://doi.org/10.1183/13993003.01477-2017

Question: What is the experience of people living with breathlessness due to medical conditions, those caring for and those treating them, with regard to quality of life and the nature of clinical interactions? Methods: Electronic databases (Ovid MED... Read More about Living with breathlessness: a systematic literature review and qualitative synthesis.

Change in Physiological Variables in the Last Two Weeks of Life: An Observational Study of Hospitalized Adults With Heart Failure (2018)
Journal Article
Taylor, P., Crouch, S., Howell, D. A., Dowding, D. W., & Johnson, M. J. (2018). Change in Physiological Variables in the Last Two Weeks of Life: An Observational Study of Hospitalized Adults With Heart Failure. Journal of pain and symptom management, 55(5), 1335-1340. https://doi.org/10.1016/j.jpainsymman.2018.01.006

© 2018 American Academy of Hospice and Palliative Medicine Context: Recognition of dying is a difficult task in end-stage heart failure, yet it remains an important clinical skill in providing good palliative care to these patients. Objectives: To us... Read More about Change in Physiological Variables in the Last Two Weeks of Life: An Observational Study of Hospitalized Adults With Heart Failure.

Postmortem ICD interrogation in mode of death classification (2018)
Journal Article
Nikolaidou, T., Johnson, M. J., Ghosh, J. M., Marincowitz, C., Shah, S., Lammiman, M. J., Schilling, R. J., & Clark, A. L. (2018). Postmortem ICD interrogation in mode of death classification. Journal of Cardiovascular Electrophysiology, 29(4), 573-583. https://doi.org/10.1111/jce.13414

© 2018 Wiley Periodicals, Inc. Background: The definition of sudden death due to arrhythmia relies on the time interval between onset of symptoms and death. However, not all sudden deaths are due to arrhythmia. In patients with an implantable cardiov... Read More about Postmortem ICD interrogation in mode of death classification.

One evidence base; three stories: do opioids relieve chronic breathlessness? (2017)
Journal Article
Ekstrom, M., Currow, D. C., Johnson, M. J., Ekström, M., Bajwah, S., Bland, J. M., Currow, D., Hussain, J., & Johnson, M. (2018). One evidence base; three stories: do opioids relieve chronic breathlessness?. Thorax, 73(1), 88-90. https://doi.org/10.1136/thoraxjnl-2016-209868

Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/. The efficacy of low-dose systemic opioids for chronic br... Read More about One evidence base; three stories: do opioids relieve chronic breathlessness?.

Insights from Australians with respiratory disease living in the community with experience of self-managing through an emergency department 'near miss' for breathlessness: A strengths-based qualitative study (2017)
Journal Article
Luckett, T., Phillips, J., Johnson, M., Garcia, M., Bhattarai, P., Carrieri-Kohlman, V., Hutchinson, A., Disler, R. T., Currow, D., Agar, M., Ivynian, S., Chye, R., Newton, P. J., & Davidson, P. M. (2017). Insights from Australians with respiratory disease living in the community with experience of self-managing through an emergency department 'near miss' for breathlessness: A strengths-based qualitative study. BMJ open, 7(12), e017536. https://doi.org/10.1136/bmjopen-2017-017536

Objectives Breathlessness ‘crises’ in people with chronic respiratory conditions are a common precipitant for emergency department (ED) presentations, many of which might be avoided through improved self-management and support. This study sought insi... Read More about Insights from Australians with respiratory disease living in the community with experience of self-managing through an emergency department 'near miss' for breathlessness: A strengths-based qualitative study.

Psychometric validation of the needs assessment tool: Progressive disease in interstitial lung disease (2017)
Journal Article
Johnson, M. J., Jamali, A., Ross, J., Fairhurst, C., Boland, J., Reigada, C., Hart, S. P., Grande, G., Currow, D. C., Wells, A. U., Papadopoulos, T., Bajwah, S., Bland, J. M., & Yorke, J. (2018). Psychometric validation of the needs assessment tool: Progressive disease in interstitial lung disease. Thorax, 73(9), 880-883. https://doi.org/10.1136/thoraxjnl-2017-210911

© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted. The inter-rater/test-retest reliability and construct validity... Read More about Psychometric validation of the needs assessment tool: Progressive disease in interstitial lung disease.

Conference presentation in palliative medicine: Predictors of subsequent publication (2017)
Journal Article
Hanchanale, S., Kerr, M., Ashwood, P., Curran, E., Ekstrom, M., Allen, S., Currow, D., & Johnson, M. J. (2018). Conference presentation in palliative medicine: Predictors of subsequent publication. BMJ Supportive & Palliative Care, 8(1), 73-77. https://doi.org/10.1136/bmjspcare-2017-001425

© 2018 Article author(s) (or their employer(s) unless otherwise stated in the text of the article). All rights reserved. Objectives Concerns have been raised about poor-quality palliative care research and low publication rate from conference abstrac... Read More about Conference presentation in palliative medicine: Predictors of subsequent publication.

Respiratory adverse effects of opioids for breathlessness: a systematic review and meta-analysis (2017)
Journal Article
Verberkt, C. A., van den Beuken-van Everdingen, M. H., Schols, J. M., Datla, S., Dirksen, C. D., Johnson, M. J., van Kuijk, S. M., Wouters, E. F., & Janssen, D. J. (2017). Respiratory adverse effects of opioids for breathlessness: a systematic review and meta-analysis. European respiratory journal, 50(5), 1701153. https://doi.org/10.1183/13993003.01153-2017

Background: Previous studies have shown that opioids can reduce chronic breathlessness in advanced disease. However, physicians remain reluctant to prescribe opioids for these patients, commonly due to fear of respiratory adverse effects. Aim: To sys... Read More about Respiratory adverse effects of opioids for breathlessness: a systematic review and meta-analysis.

The independent association of overweight and obesity with breathlessness in adults: a cross-sectional, population-based study (2017)
Journal Article
Currow, D. C., Dal Grande, E., Sidhu, C., Ekström, M., & Johnson, M. J. (2017). The independent association of overweight and obesity with breathlessness in adults: a cross-sectional, population-based study. European respiratory journal, 50(3), Article 1700558. https://doi.org/10.1183/13993003.00558-2017

Obesity is an independent risk factor for chronic breathlessness and should be assessed in people with this symptom.

Contributions of a hand-held fan to self-management of chronic breathlessness (2017)
Journal Article
Luckett, T., Phillips, J., Johnson, M. J., Farquhar, M., Swan, F., Assen, T., Bhattarai, P., & Booth, S. (2017). Contributions of a hand-held fan to self-management of chronic breathlessness. European respiratory journal, 50(2), Article 1700262. https://doi.org/10.1183/13993003.00262-2017

© ERS 2017. This study explored the benefits of a hand-held fan as perceived by patients with chronic breathlessness and their carers. A secondary multimethod analysis was conducted of interview data collected in three clinical trials. Two researcher... Read More about Contributions of a hand-held fan to self-management of chronic breathlessness.

Pharmacovigilance in hospice/palliative care: Net effect of haloperidol for nausea or vomiting (2017)
Journal Article
Digges, M., Hussein, A., Wilcock, A., Crawford, G. B., Boland, J. W., Agar, M. R., Sinnarajah, A., Currow, D. C., & Johnson, M. J. (2018). Pharmacovigilance in hospice/palliative care: Net effect of haloperidol for nausea or vomiting. Journal of palliative medicine, 21(1), 37-43. https://doi.org/10.1089/jpm.2017.0159

Background Haloperidol is widely prescribed as an anti-emetic in patients receiving palliative care, but there is limited evidence to support and refine its use. Objective To explore the immediate and short-term net clinical effects of haloperidol wh... Read More about Pharmacovigilance in hospice/palliative care: Net effect of haloperidol for nausea or vomiting.

Care of the dying : a qualitative exploration of foundation year doctors’ experiences (2017)
Journal Article
Redman, M., Pearce, J., Gajebasia, S., Johnson, M., & Finn, G. (2017). Care of the dying : a qualitative exploration of foundation year doctors’ experiences. Medical Education, 51(10), 1025-1036. https://doi.org/10.1111/medu.13358

Context Foundation Year doctors (FYs), who are newly qualified, are expected to provide care for dying patients. Experiences at this early mandatory stage of training may form the foundation for future encounters, but little is documented about wha... Read More about Care of the dying : a qualitative exploration of foundation year doctors’ experiences.

A pragmatic, phase III, multisite, double-blind, placebo-controlled, parallel-arm, dose increment randomised trial of regular, low-dose extended-release morphine for chronic breathlessness: Breathlessness, Exertion And Morphine Sulfate (BEAMS) study protocol (2017)
Journal Article
Currow, D., Watts, G. J., Johnson, M., McDonald, C. F., Miners, J. O., Somogyi, A. A., Denehy, L., McCaffrey, N., Eckert, D. J., McCloud, P., Louw, S., Lam, L., Greene, A., Fazekas, B., Clark, K. C., Fong, K., Agar, M. R., Joshi, R., Kilbreath, S., Ferreira, D., & Ekström, M. (2017). A pragmatic, phase III, multisite, double-blind, placebo-controlled, parallel-arm, dose increment randomised trial of regular, low-dose extended-release morphine for chronic breathlessness: Breathlessness, Exertion And Morphine Sulfate (BEAMS) study protocol. BMJ open, 7(7), 1-18. https://doi.org/10.1136/bmjopen-2017-018100

© Article author(s). Introduction Chronic breathlessness is highly prevalent and distressing to patients and families. No medication is registered for its symptomatic reduction. The strongest evidence is for regular, low-dose, extended-release (ER) o... Read More about A pragmatic, phase III, multisite, double-blind, placebo-controlled, parallel-arm, dose increment randomised trial of regular, low-dose extended-release morphine for chronic breathlessness: Breathlessness, Exertion And Morphine Sulfate (BEAMS) study protocol.