Skip to main content

Research Repository

Advanced Search

All Outputs (217)

Clinical decision making in the recognition of dying: a qualitative interview study (2017)
Journal Article
Taylor, P., Dowding, D., & Johnson, M. (2017). Clinical decision making in the recognition of dying: a qualitative interview study. BMC Palliative Care, 16(11), Article ARTN 11. https://doi.org/10.1186/s12904-016-0179-3

Background: Recognising dying is an essential clinical skill for general and palliative care professionals alike. Despite the high importance, both identification and good clinical care of the dying patient remains extremely difficult and often contr... Read More about Clinical decision making in the recognition of dying: a qualitative interview study.

Palliative care and Parkinson's disease : meeting summary and recommendations for clinical research (2017)
Journal Article
Kluger, B. M., Galifianakis, N. B., Carter, J. H., Johnson, M. J., Richfield, E. W., Kutner, J. S., …Miyasaki, J. (2017). Palliative care and Parkinson's disease : meeting summary and recommendations for clinical research. Parkinsonism and Related Disorders, 37, 19-26. https://doi.org/10.1016/j.parkreldis.2017.01.008

Introduction: Palliative care is an approach to caring for patients and families affected by serious illnesses that focuses on the relief of suffering through the management of medical symptoms, psychosocial issues, advance care planning and spiritua... Read More about Palliative care and Parkinson's disease : meeting summary and recommendations for clinical research.

Somatostatin analogues compared to placebo and other pharmacological agents in the management of symptoms of inoperable malignant bowel obstruction: a systematic review (2016)
Journal Article
Obita, G. P., Boland, E. G., Currow, D. C., Johnson, M. J., & Boland, J. W. (2016). Somatostatin analogues compared to placebo and other pharmacological agents in the management of symptoms of inoperable malignant bowel obstruction: a systematic review. Journal of pain and symptom management, 52(6), 901-919. https://doi.org/10.1016/j.jpainsymman.2016.05.032

Context Somatostatin analogues are commonly used to relieve symptoms in malignant bowel obstruction (MBO) but are more expensive than other antisecretory agents. Objectives To evaluate the evidence of effectiveness of somatostatin analogues compared... Read More about Somatostatin analogues compared to placebo and other pharmacological agents in the management of symptoms of inoperable malignant bowel obstruction: a systematic review.

Missing data in randomized controlled trials testing palliative interventions pose a significant risk of bias and loss of power: a systematic review and meta-analyses (2016)
Journal Article
Hussain, J. A., White, I. R., Langan, D., Johnson, M. J., Currow, D. C., Torgerson, D. J., & Bland, M. (2016). Missing data in randomized controlled trials testing palliative interventions pose a significant risk of bias and loss of power: a systematic review and meta-analyses. Journal of clinical epidemiology, 74, 57-65. https://doi.org/10.1016/j.jclinepi.2015.12.003

Objectives To assess the risk posed by missing data (MD) to the power and validity of trials evaluating palliative interventions. Study Design and Setting A systematic review of MD in published randomized controlled trials (RCTs) of palliative interv... Read More about Missing data in randomized controlled trials testing palliative interventions pose a significant risk of bias and loss of power: a systematic review and meta-analyses.

Content and quality of websites supporting self-management of chronic breathlessness in advanced illness: a systematic review (2016)
Journal Article
Luckett, T., Disler, R., Hosie, A., Johnson, M., Davidson, P., Currow, D., …Phillips, J. (2016). Content and quality of websites supporting self-management of chronic breathlessness in advanced illness: a systematic review. NPJ Primary Care Respiratory Medicine, 26(1), Article ARTN 16025. https://doi.org/10.1038/npjpcrm.2016.25

Chronic breathlessness is a common, burdensome and distressing symptom in many advanced chronic illnesses. Self-management strategies are essential to optimise treatment, daily functioning and emotional coping. People with chronic illness commonly se... Read More about Content and quality of websites supporting self-management of chronic breathlessness in advanced illness: a systematic review.

A mixed-methods, randomized controlled, feasibility trial to inform the design of a phase 3 trial to test the effect of the hand-held fan on physical activity and carer anxiety in patients with refractory breathlessness (2016)
Journal Article
Johnson, M. J., Booth, S., Currow, D. C., Lam, L. T., & Phillips, J. L. (2016). A mixed-methods, randomized controlled, feasibility trial to inform the design of a phase 3 trial to test the effect of the hand-held fan on physical activity and carer anxiety in patients with refractory breathlessness. Journal of pain and symptom management, 51(5), 807-815. https://doi.org/10.1016/j.jpainsymman.2015.11.026

Context The handheld fan is an inexpensive and safe way to provide facial airflow, which may reduce the sensation of chronic refractory breathlessness, a frequently encountered symptom. Objectives To test the feasibility of developing an adequately p... Read More about A mixed-methods, randomized controlled, feasibility trial to inform the design of a phase 3 trial to test the effect of the hand-held fan on physical activity and carer anxiety in patients with refractory breathlessness.

The adaptation, face, and content validation of a needs assessment tool: progressive disease for people with interstitial lung disease (2016)
Journal Article
Boland, J. W., Reigada, C., Yorke, J., Hart, S. P., Bajwah, S., Ross, J., …Johnson, M. J. (2016). The adaptation, face, and content validation of a needs assessment tool: progressive disease for people with interstitial lung disease. Journal of palliative medicine, 19(5), 549-555. https://doi.org/10.1089/jpm.2015.0355

Background: Irrreversible interstitial lung disease (ILD) is associated with high morbidity and mortality. Palliative care needs of patients and caregivers are not routinely assessed; there is no tool to identify needs and triage support in clinical... Read More about The adaptation, face, and content validation of a needs assessment tool: progressive disease for people with interstitial lung disease.

Family caregivers who would be unwilling to provide care at the end of life again: findings from the Health Survey for England population survey (2016)
Journal Article
Johnson, M. J., Allgar, V., Macleod, U., Jones, A., Oliver, S., & Currow, D. (2016). Family caregivers who would be unwilling to provide care at the end of life again: findings from the Health Survey for England population survey. PLoS ONE, 11(1), e0146960. https://doi.org/10.1371/journal.pone.0146960

Background Family caregivers provide significant care at the end of life. We aimed to describe caregiver characteristics, and of those unwilling to repeat this role under the same circumstances. Methods Observational study of adults in private househ... Read More about Family caregivers who would be unwilling to provide care at the end of life again: findings from the Health Survey for England population survey.

Breathlessness in the elderly during the last year of life sufficient to restrict activity (2016)
Journal Article
Johnson, M. J., Bland, J. M., Gahbauer, E. A., Ekström, M., Sinnarajah, A., Gill, T. M., & Currow, D. (2016). Breathlessness in the elderly during the last year of life sufficient to restrict activity. Journal of the American Geriatrics Society, 64(1), 73-80. https://doi.org/10.1111/jgs.13865

OBJECTIVES: Breathlessness is prevalent in older people. Symptom control at the end of life is important. This study investigated relationships between age, clinical characteristics and breathlessness sufficient to have people spend at least one half... Read More about Breathlessness in the elderly during the last year of life sufficient to restrict activity.

Effects of low dose morphine on perceived sleep quality in patients with refractory breathlessness : a hypothesis generating study (2015)
Journal Article
Martins, R. T., Currow, D., Abernethy, A. P., Johnson, M. J., Toson, B., & Eckert, D. J. (2016). Effects of low dose morphine on perceived sleep quality in patients with refractory breathlessness : a hypothesis generating study. Respirology : official journal of the Asian Pacific Society of Respirology, 21(2), 386-391. https://doi.org/10.1111/resp.12681

© 2015 Asian Pacific Society of Respirology. Background and objective The management of chronic refractory breathlessness is one of the indications for regular low-dose (≤30 mg/24 h) oral sustained release morphine. Morphine may disrupt sleep in some... Read More about Effects of low dose morphine on perceived sleep quality in patients with refractory breathlessness : a hypothesis generating study.

Blinded patient preference for morphine compared to placebo in the setting of chronic refractory breathlessness – an exploratory study (2015)
Journal Article
Ferreira, D. H., Silva, J. P., Quinn, S., Abernethy, A. P., Johnson, M. J., Oxberry, S. G., & Currow, D. C. (2016). Blinded patient preference for morphine compared to placebo in the setting of chronic refractory breathlessness – an exploratory study. Journal of pain and symptom management, 51(2), 247-254. https://doi.org/10.1016/j.jpainsymman.2015.10.005

Context Patients’ preference for morphine therapy has received little attention in the setting of chronic refractory breathlessness. However, this is one important factor in considering longer term therapy. Objectives The aim of this secondary analys... Read More about Blinded patient preference for morphine compared to placebo in the setting of chronic refractory breathlessness – an exploratory study.

Does the use of specialist palliative care services modify the effect of socioeconomic status on place of death? A systematic review (2015)
Journal Article
Chen, H., Nicolson, D. J., MacLeod, U., Allgar, V., Dalgliesh, C., & Johnson, M. (2016). Does the use of specialist palliative care services modify the effect of socioeconomic status on place of death? A systematic review. Palliative medicine, 30(5), 434-445. https://doi.org/10.1177/0269216315602590

© SAGE Publications. Background: Cancer patients in lower socioeconomic groups are significantly less likely to die at home and experience more barriers to access to palliative care. It is unclear whether receiving palliative care may mediate the eff... Read More about Does the use of specialist palliative care services modify the effect of socioeconomic status on place of death? A systematic review.

A randomised controlled trial of three or one breathing technique training sessions for breathlessness in people with malignant lung disease (2015)
Journal Article
Johnson, M. J., Kanaan, M., Richardson, G., Nabb, S., Torgerson, D., English, A., …Booth, S. (2015). A randomised controlled trial of three or one breathing technique training sessions for breathlessness in people with malignant lung disease. BMC medicine, 13(1), Article 213. https://doi.org/10.1186/s12916-015-0453-x

© Johnson et al. Background: About 90 % of patients with intra-thoracic malignancy experience breathlessness. Breathing training is helpful, but it is unknown whether repeated sessions are needed. The present study aims to test whether three sessions... Read More about A randomised controlled trial of three or one breathing technique training sessions for breathlessness in people with malignant lung disease.

Does home oxygen therapy (HOT) in addition to standard care reduce disease severity and improve symptoms in people with chronic heart failure? A randomised trial of home oxygen therapy for patients with chronic heart failure (2015)
Journal Article
Clark, A. L., Johnson, M., Fairhurst, C., Torgerson, D., Cockayne, S., Rodgers, S., …Greenstone, M. (2015). Does home oxygen therapy (HOT) in addition to standard care reduce disease severity and improve symptoms in people with chronic heart failure? A randomised trial of home oxygen therapy for patients with chronic heart failure. Health Technology Assessment, 19(75), 1-120. https://doi.org/10.3310/hta19750

Background: Home oxygen therapy (HOT) is commonly used for patients with severe chronic heart failure (CHF) who have intractable breathlessness. There is no trial evidence to support its use. Objectives: To detect whether or not there was a quality-... Read More about Does home oxygen therapy (HOT) in addition to standard care reduce disease severity and improve symptoms in people with chronic heart failure? A randomised trial of home oxygen therapy for patients with chronic heart failure.

Preferred and actual place of death in haematological malignancy (2015)
Journal Article
Howell, D. A., Wang, H. I., Roman, E., Smith, A. G., Patmore, R., Johnson, M. J., …Howard, M. (2017). Preferred and actual place of death in haematological malignancy. BMJ supportive & palliative care, 7(2), 150-157. https://doi.org/10.1136/bmjspcare-2014-000793

Objectives Home is considered the preferred place of death for many, but patients with haematological malignancies (leukaemias, lymphomas and myeloma) die in hospital more often than those with other cancers and the reasons for this are not wholly un... Read More about Preferred and actual place of death in haematological malignancy.

Magnetoencephalography to investigate central perception of exercise-induced breathlessness in people with chronic lung disease: A feasibility pilot (2015)
Journal Article
Johnson, M. J., Simpson, M. I., Currow, D. C., Millman, R. E., Hart, S. P., & Green, G. (2015). Magnetoencephalography to investigate central perception of exercise-induced breathlessness in people with chronic lung disease: A feasibility pilot. BMJ open, 5(6), Article ARTN e007535. https://doi.org/10.1136/bmjopen-2014-007535

Objectives: Neuroimaging in chronic breathlessness is challenging. The study objective was to test the feasibility of magnetoencephalography (MEG) for functional neuroimaging of people with chronic breathlessness. Design: Feasibility pilot study. Set... Read More about Magnetoencephalography to investigate central perception of exercise-induced breathlessness in people with chronic lung disease: A feasibility pilot.

Can variability in the effect of opioids on refractory breathlessness be explained by genetic factors? (2015)
Journal Article
Currow, D. C., Quinn, S., Ekström, M., Kaasa, S., Johnson, M. J., Somogyi, A. A., & Klepstad, P. (2015). Can variability in the effect of opioids on refractory breathlessness be explained by genetic factors?. BMJ open, 5(5), e006818-e006818. https://doi.org/10.1136/bmjopen-2014-006818

© 2015, BMJ Publishing Group. All rights reserved. Objectives: Opioids modulate the perception of breathlessness with a considerable variation in response, with poor correlation between the required opioid dose and symptom severity. The objective of... Read More about Can variability in the effect of opioids on refractory breathlessness be explained by genetic factors?.

Patient and health care professional decision-making to commence and withdraw from renal dialysis: A systematic review of qualitative research (2015)
Journal Article
Hussain, J. A., Flemming, K., Murtagh, F. E., & Johnson, M. J. (2015). Patient and health care professional decision-making to commence and withdraw from renal dialysis: A systematic review of qualitative research. Clinical journal of the American Society of Nephrology, 10(7), 1201-1215. https://doi.org/10.2215/cjn.11091114

Background and objectives. To ensure decisions to start and stop dialysis in end stage kidney disease are shared, the factors that affect patients and healthcare professionals in making such decisions need to be understood. This systematic review aim... Read More about Patient and health care professional decision-making to commence and withdraw from renal dialysis: A systematic review of qualitative research.