All Outputs (2)

Transcriptional regulation of the sodium channel gene (SCN5A) by GATA4 in human heart (2016)
Journal Article
Tarradas, A., Pinsach-Abuin, M., Mackintosh, C., Llorà-Batlle, O., Pérez-Serra, A., Batlle, M., Pérez-Villa, F., Zimmer, T., Garcia-Bassets, I., Brugada, R., Beltran-Alvarez, P., & Pagans, S. (2017). Transcriptional regulation of the sodium channel gene (SCN5A) by GATA4 in human heart. Journal of Molecular and Cellular Cardiology, 102, 74-82. https://doi.org/10.1016/j.yjmcc.2016.10.013

Aberrant expression of the sodium channel gene (SCN5A) has been proposed to disrupt cardiac action potential and cause human cardiac arrhythmias, but the mechanisms of SCN5A gene regulation and dysregulation still remain largely unexplored. To gain i... Read More about Transcriptional regulation of the sodium channel gene (SCN5A) by GATA4 in human heart.

Mapping arginine methylation in the human body and cardiac disease (2016)
Journal Article
Onwuli, D. O., Rigau-Roca, L., Cawthorne, C., & Beltran-Alvarez, P. (2017). Mapping arginine methylation in the human body and cardiac disease. Proteomics. Clinical applications, 11(1-2), Article ARTN 1600106. https://doi.org/10.1002/prca.201600106

Purpose Arginine methylation (ArgMe) is one of the most ubiquitous post-translational modifications, and hundreds of proteins undergo ArgMe in e.g. brain. However, the scope of ArgMe in many tissues, including the heart, is currently under explored.... Read More about Mapping arginine methylation in the human body and cardiac disease.