New insights to the role of aryl hydrocarbon receptor in bone phenotype and in dioxin-induced modulation of bone microarchitecture and material properties

Herlin, Maria; Finnilä, Mikko A.J.; Zioupos, Peter; Aula, Antti; Risteli, Juha; Miettinen, Hanna M.; Jämsä, Timo; Tuukkanen, Juha; Korkalainen, Merja; Håkansson, Helen; Viluksela, Matti

doi:10.1016/j.taap.2013.09.002

All Outputs (4)

Development of a strain rate dependent material model of human cortical bone for computer-aided reconstruction of injury mechanisms (2013)
Journal Article
Asgharpour, Z., Zioupos, P., Graw, M., & Peldschus, S. (2014). Development of a strain rate dependent material model of human cortical bone for computer-aided reconstruction of injury mechanisms. Forensic Science International, 236, 109-116. https://doi.org/10.1016/j.forsciint.2013.11.010

Computer-aided methods such as finite-element simulation offer a great potential in the forensic reconstruction of injury mechanisms. Numerous studies have been performed on understanding and analysing the mechanical properties of bone and the mechan... Read More about Development of a strain rate dependent material model of human cortical bone for computer-aided reconstruction of injury mechanisms.

Forensic biomechanics (2013)
Journal Article
Zioupos, P. (2014). Forensic biomechanics. Journal of the mechanical behavior of biomedical materials, 33(1), 1-2. https://doi.org/10.1016/j.jmbbm.2013.11.005

Determining 'Age at death' for forensic purposes using human bone by a laboratory-based biomechanical analytical method (2013)
Journal Article
Zioupos, P., Williams, A., Christodoulou, G., & Giles, R. (2014). Determining 'Age at death' for forensic purposes using human bone by a laboratory-based biomechanical analytical method. Journal of the mechanical behavior of biomedical materials, 33(1), 109-123. https://doi.org/10.1016/j.jmbbm.2013.10.015

Determination of age-at-death (AAD) is an important and frequent requirement in contemporary forensic science and in the reconstruction of past populations and societies from their remains. Its estimation is relatively straightforward and accurate (±... Read More about Determining 'Age at death' for forensic purposes using human bone by a laboratory-based biomechanical analytical method.

New insights to the role of aryl hydrocarbon receptor in bone phenotype and in dioxin-induced modulation of bone microarchitecture and material properties (2013)
Journal Article
Herlin, M., Finnilä, M. A., Zioupos, P., Aula, A., Risteli, J., Miettinen, H. M., …Viluksela, M. (2013). New insights to the role of aryl hydrocarbon receptor in bone phenotype and in dioxin-induced modulation of bone microarchitecture and material properties. Toxicology and Applied Pharmacology, 273(1), 219-226. https://doi.org/10.1016/j.taap.2013.09.002

Bone is a target for high affinity aryl hydrocarbon receptor (AHR) ligands, such as dioxins. Although bone morphology, mineral density and strength are sensitive endpoints of dioxin toxicity, less is known about effects on bone microarchitecture and... Read More about New insights to the role of aryl hydrocarbon receptor in bone phenotype and in dioxin-induced modulation of bone microarchitecture and material properties.