All Outputs (3)

Expression and localization of creatine kinase in the preimplantation embryo (2012)
Journal Article
Forsey, K. E., Ellis, P. J., Sargent, C. A., Sturmey, R. G., & Leese, H. J. (2013). Expression and localization of creatine kinase in the preimplantation embryo. Molecular Reproduction and Development, 80(3), 185-192. https://doi.org/10.1002/mrd.22146

Creatine Kinase (CK) catalyses the “creatine shuttle,” the reversible conversion of creatine phosphate to creatine with the liberation of ATP. This article examines the potential role of the creatine shuttle in the provision of ATP during mouse preim... Read More about Expression and localization of creatine kinase in the preimplantation embryo.

Oocyte developmental failure in response to elevated nonesterified fatty acid concentrations: mechanistic insights (2012)
Journal Article
Van Hoeck, V., Leroy, J. L. M. R., Arias Alvarez, M., Rizos, D., Gutierrez-Adan, A., Schnorbusch, K., Bols, P. E. J., Leese, H. J., & Sturmey, R. G. (2013). Oocyte developmental failure in response to elevated nonesterified fatty acid concentrations: mechanistic insights. Reproduction, 145(1), 33-44. https://doi.org/10.1530/REP-12-0174

Elevated plasma nonesterified fatty acid (NEFA) concentrations are associated with negative energy balance and metabolic disorders such as obesity and type II diabetes. Such increased plasma NEFA concentrations induce changes in the microenvironment... Read More about Oocyte developmental failure in response to elevated nonesterified fatty acid concentrations: mechanistic insights.

Variable imprinting of the MEST gene in human preimplantation embryos (2012)
Journal Article
Huntriss, J. D., Hemmings, K. E., Hinkins, M., Rutherford, A. J., Sturmey, R. G., Elder, K., & Picton, H. M. (2013). Variable imprinting of the MEST gene in human preimplantation embryos. European Journal of Human Genetics, 21(1), 40-47. https://doi.org/10.1038/ejhg.2012.102

There is evidence that expression and methylation of the imprinted paternally expressed gene 1/mesoderm-specific transcript homologue (PEG1/MEST) gene may be affected by assisted reproductive technologies (ARTs) and infertility. In this study, we sou... Read More about Variable imprinting of the MEST gene in human preimplantation embryos.