Identification of a novel, actin-rich structure, the actin nodule, in the early stages of platelet spreading

Calaminus, S. D. J.; Calaminus, Simon D J; Thomas, S.; McCarty, O. J. T.; Machesky, L. M.; McCarty, O. J T; Watson, S. P.

doi:10.1111/j.1538-7836.2008.03141.x

All Outputs (23)

G-protein coupled and ITAM receptor regulation of the formin FHOD1 through Rho Kinase in platelets (2011)
Journal Article
Thomas, S. G., Calaminus, S., Machesky, L. M., Alberts, A. S., & Watson, S. P. (2011). G-protein coupled and ITAM receptor regulation of the formin FHOD1 through Rho Kinase in platelets. Journal of thrombosis and haemostasis : JTH, 9(8), 1648-1651. https://doi.org/10.1111/j.1538-7836.2011.04357.x

Actin polymerization driven by WASH causes V-ATPase retrieval and vesicle neutralization before exocytosis (2011)
Journal Article
Carnell, M., Zech, T., Calaminus, S. D., Ura, S., Hagedorn, M., Johnston, S. A., May, R. C., Soldati, T., Machesky, L. M., & Insall, R. H. (2011). Actin polymerization driven by WASH causes V-ATPase retrieval and vesicle neutralization before exocytosis. Journal of Cell Biology, 193(5), 831-839. https://doi.org/10.1083/jcb.201009119

WASP and SCAR homologue (WASH) is a recently identified and evolutionarily conserved regulator of actin polymerization. In this paper, we show that WASH coats mature Dictyostelium discoideum lysosomes and is essential for exocytosis of indigestible m... Read More about Actin polymerization driven by WASH causes V-ATPase retrieval and vesicle neutralization before exocytosis.

Identification of a novel, actin-rich structure, the actin nodule, in the early stages of platelet spreading (2008)
Journal Article
Calaminus, S. D. J., Thomas, S., McCarty, O. J. T., Machesky, L. M., & Watson, S. P. (2008). Identification of a novel, actin-rich structure, the actin nodule, in the early stages of platelet spreading. Journal of thrombosis and haemostasis : JTH, 6(11), 1944-1952. https://doi.org/10.1111/j.1538-7836.2008.03141.x

During platelet spreading, the actin cytoskeleton undergoes marked changes, forming filopodia, lamellipodia and stress fibres. In the present study, we report the identification of a novel actin-rich structure, termed an actin nodule, which appears p... Read More about Identification of a novel, actin-rich structure, the actin nodule, in the early stages of platelet spreading.