Association of FcγRIIa (CD32a) with lipid rafts regulates ligand binding activity
(2009)
Journal Article
Bournazos, S., Hart, S. P., Chamberlain, L. H., Glennie, M. J., & Dransfield, I. (2009). Association of FcγRIIa (CD32a) with lipid rafts regulates ligand binding activity. Journal of Immunology, 182(12), 8026-8036. https://doi.org/10.4049/jimmunol.0900107
Binding of Igs to myeloid cells via FcR is a key event in the control of innate and acquired immunity. FcγRIIa (CD32a) is a receptor for multivalent IgG expressed predominantly by myeloid cells, and its association with microdomains rich in cholester... Read More about Association of FcγRIIa (CD32a) with lipid rafts regulates ligand binding activity.