All Outputs (2)

Tumors hamper the immunogenic competence of CD4+T cell-directed dendritic cell vaccination (2007)
Journal Article
Zimmermann, V. S., Casati, A., Schiering, C., Caserta, S., Hess Michelini, R., Basso, V., & Mondino, A. (2007). Tumors hamper the immunogenic competence of CD4+T cell-directed dendritic cell vaccination. Journal of Immunology, 179(5), 2899-2909. https://doi.org/10.4049/jimmunol.179.5.2899

Dendritic cells loaded with tumor-derived peptides induce protective CTL responses and are under evaluation in clinical trails. We report in this study that prophylactic administration of dendritic cells loaded with a MHC class II-restricted peptide... Read More about Tumors hamper the immunogenic competence of CD4+T cell-directed dendritic cell vaccination.

Memories are made of this: synergy of T cell receptor and cytokine signals in CD4+ central memory cell survival (2007)
Journal Article
Caserta, S., & Zamoyska, R. (2007). Memories are made of this: synergy of T cell receptor and cytokine signals in CD4+ central memory cell survival. Trends in immunology, 28(6), 245-248. https://doi.org/10.1016/j.it.2007.04.006

The ability of the immune system to 'remember' a previous encounter with antigen is the hallmark of the adaptive immune response. The signals required for CD4 + memory T cell survival are not well understood, and a recent paper lends new biochemical... Read More about Memories are made of this: synergy of T cell receptor and cytokine signals in CD4+ central memory cell survival.