All Outputs (8)

Smart active antibiotic nanocarriers with protease surface functionality can overcome biofilms of resistant bacteria (2020)
Journal Article
Weldrick, P. J., Hardman, M. J., & Paunov, V. N. (2021). Smart active antibiotic nanocarriers with protease surface functionality can overcome biofilms of resistant bacteria. Materials Chemistry Frontiers, 5(2), 961-972. https://doi.org/10.1039/d0qm00874e

Treating bacterial infections with species demonstrating antibiotic resistance to the chosen antibiotic is often hindered due to the ability of certain bacteria to grow biofilms where they can effectively hide and resist the antibiotic action. We rep... Read More about Smart active antibiotic nanocarriers with protease surface functionality can overcome biofilms of resistant bacteria.

High-throughput fabrication of hepatic cell clusteroids with enhanced growth and functionality for tissue engineering applications (2020)
Journal Article
Wang, A., Madden, L. A., & Paunov, V. N. (2020). High-throughput fabrication of hepatic cell clusteroids with enhanced growth and functionality for tissue engineering applications. Materials Advances, 1(8), 3022-3032. https://doi.org/10.1039/d0ma00635a

Culturing of cells as three-dimensional (3D) clusters can enhance in vitro tests for basic biological research as well as for therapeutics development. Such 3D culture models, however, are often more complicated, cumbersome and expensive than two-dim... Read More about High-throughput fabrication of hepatic cell clusteroids with enhanced growth and functionality for tissue engineering applications.

Advanced biomedical applications based on emerging 3D cell culturing platforms (2020)
Journal Article
Wang, A., Madden, L. A., & Paunov, V. N. (2020). Advanced biomedical applications based on emerging 3D cell culturing platforms. Journal of Materials Chemistry B, 8(46), 10487-10501. https://doi.org/10.1039/d0tb01658f

It is of great value to develop reliable in vitro models for cell biology and toxicology. However, ethical issues and the decreasing number of donors restrict the further use of traditional animal models in various fields, including the emerging fiel... Read More about Advanced biomedical applications based on emerging 3D cell culturing platforms.

Bioimprint Mediated Label-Free Isolation of Pancreatic Tumor Cells from a Healthy Peripheral Blood Cell Population (2020)
Journal Article
Pelle, M., Das, A. A. K., Madden, L. A., & Paunov, V. N. (in press). Bioimprint Mediated Label-Free Isolation of Pancreatic Tumor Cells from a Healthy Peripheral Blood Cell Population. Advanced Biosystems, Article 2000054. https://doi.org/10.1002/adbi.202000054

New techniques are required for earlier diagnosis and response to treatment of pancreatic cancer. Here, a label-free approach is reported in which circulating pancreatic tumor cells are isolated from healthy peripheral blood cells via cell bioimprint... Read More about Bioimprint Mediated Label-Free Isolation of Pancreatic Tumor Cells from a Healthy Peripheral Blood Cell Population.

Toxicity of polyelectrolyte-functionalized titania nanoparticles in zebrafish (Danio rerio) embryos (2020)
Journal Article
Arabeyyat, Z. H., Al-Awady, M. J., Greenway, G. M., Paunov, V. N., & Rotchell, J. M. (2020). Toxicity of polyelectrolyte-functionalized titania nanoparticles in zebrafish (Danio rerio) embryos. SN Applied Sciences, 2(7), Article 1312. https://doi.org/10.1007/s42452-020-3137-x

We investigated the effects of short-term exposure of bare TiO2NPs and polyelectrolyte-coated TiO2NPs in the 5–25nm size range, at relatively high concentrations (of 500 and 1000mg/L) under light or dark conditions, in D. rerio embryos. The biologica... Read More about Toxicity of polyelectrolyte-functionalized titania nanoparticles in zebrafish (Danio rerio) embryos.

Silver nanoparticles in Zebrafish (Danio rerio) embryos: Uptake, growth and molecular responses (2020)
Journal Article
Qiang, L., Arabeyyat, Z. H., Xin, Q., Paunov, V. N., Dale, I. J., Lloyd Mills, R. I., Rotchell, J. M., & Cheng, J. (2020). Silver nanoparticles in Zebrafish (Danio rerio) embryos: Uptake, growth and molecular responses. International Journal of Molecular Sciences, 21(5), Article 1876. https://doi.org/10.3390/ijms21051876

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Silver nanoparticles (AgNPs) are widely used in commercial applications as antimicrobial agents, but there have recently been increasing concerns raised about their possible environmental and... Read More about Silver nanoparticles in Zebrafish (Danio rerio) embryos: Uptake, growth and molecular responses.

Removal of Human Leukemic Cells from Peripheral Blood Mononuclear Cells by Cell Recognition Chromatography with Size Matched Particle Imprints (2020)
Journal Article
Chester, R., Das, A. A. K., Medlock, J., Nees, D., Allsup, D. J., Madden, L. A., & Paunov, V. N. (2020). Removal of Human Leukemic Cells from Peripheral Blood Mononuclear Cells by Cell Recognition Chromatography with Size Matched Particle Imprints. ACS Applied Bio Materials, 3(2), 789-800. https://doi.org/10.1021/acsabm.9b00770

We report a cell recognition chromatography approach for blood cancer cell separation from healthy peripheral blood mononuclear cells (PBMCs) based on sizematched functionalized particle imprints. Negative imprints were prepared from layers of 15 μm... Read More about Removal of Human Leukemic Cells from Peripheral Blood Mononuclear Cells by Cell Recognition Chromatography with Size Matched Particle Imprints.

Surface-Modified Zinc Oxide Nanoparticles for Antialgal and Antiyeast Applications (2020)
Journal Article
Halbus, A. F., Horozov, T. S., & Paunov, V. N. (2020). Surface-Modified Zinc Oxide Nanoparticles for Antialgal and Antiyeast Applications. ACS Applied Nano Materials, 3(1), 440-451. https://doi.org/10.1021/acsanm.9b02045

We explored the factors and mechanisms of the anti-yeast and anti-algal effect of zinc oxide nanoparticles (ZnONPs) coated with zinc sulfide (ZnS), silica (SiO2), poly(sodium 4-styrene sulfonate) sodium salt (PSS) and poly(allylamine hydrochloride) (... Read More about Surface-Modified Zinc Oxide Nanoparticles for Antialgal and Antiyeast Applications.