All Outputs (2)

Evaluating trastuzumab in the treatment of HER2 positive breast cancer (2020)
Journal Article
Jaques, R., Xu, S., & Matsakas, A. (2020). Evaluating trastuzumab in the treatment of HER2 positive breast cancer. Histology and Histopathology, 35(10), 1059-1075. https://doi.org/10.14670/HH-18-221

© 2020, Histology and Histopathology. All rights reserved. The transmembrane oncoprotein HER2 is encoded by ERBB2 gene and overexpressed in around 20% of invasive breast cancers. It can be specifically targeted by Trastuzumab (Herceptin®), a humanise... Read More about Evaluating trastuzumab in the treatment of HER2 positive breast cancer.

Mesenchymal stem cell-based Smad7 gene therapy for experimental liver cirrhosis (2020)
Journal Article
Su, D., Wu, S., & Xu, S. (2020). Mesenchymal stem cell-based Smad7 gene therapy for experimental liver cirrhosis. Stem Cell Research and Therapy, 11(1), Article 395. https://doi.org/10.1186/s13287-020-01911-4

Background Bone mesenchymal stem cells (MSCs) can promote liver regeneration and inhibit inflammation and hepatic fibrosis. MSCs also can serve as a vehicle for gene therapy. Smad7 is an essential negative regulatory gene in the TGF-β1/Smad signalli... Read More about Mesenchymal stem cell-based Smad7 gene therapy for experimental liver cirrhosis.