PCSK6 and Survival in Idiopathic Pulmonary Fibrosis

Oldham, Justin M.; Allen, Richard J; Lorenzo-Salazar, Jose M.; Molyneaux, Philip L; Ma, Shwu Fan; Joseph, Chitra; Kim, John S.; Guillen-Guio, Beatriz; Hernández-Beeftink, Tamara; Kropski, Jonathan A; Huang, Yong; Lee, Cathryn T.; Adegunsoye, Ayodeji; Pugashetti, Janelle Vu; Linderholm, Angela L; Vo, Vivian; Strek, Mary E.; Jou, Jonathan; Muñoz-Barrera, Adrian; Rubio-Rodriguez, Luis A.; Hubbard, Richard; Hirani, Nik; Whyte, Moira K.B.; Hart, Simon; Nicholson, Andrew G; Lancaster, Lisa; Parfrey, Helen; Rassl, Doris; Wallace, William; Valenzi, Eleanor; Zhang, Yingze; Mychaleckyj, Josyf; Stockwell, Amy; Kaminski, Naftali; Wolters, Paul J; Molina-Molina, Maria; Banovich, Nicholas E; Fahy, William A; Martinez, Fernando J.; Hall, Ian P.; Tobin, Martin D; Maher, Toby M.; Blackwell, Timothy S; Yaspan, Brian L; Gisli Jenkins, R; Jenkins, R. Gisli; Flores, Carlos; Wain, Louise V; Noth, Imre

doi:10.1164/rccm.202205-0845OC

All Outputs (3)

High-resolution CT phenotypes in pulmonary sarcoidosis: a multinational Delphi consensus study (2023)
Journal Article
Desai, S. R., Sivarasan, N., Johannson, K. A., George, P. M., Culver, D. A., Devaraj, A., …Inoue, Y. (in press). High-resolution CT phenotypes in pulmonary sarcoidosis: a multinational Delphi consensus study. The lancet. Respiratory medicine, https://doi.org/10.1016/S2213-2600%2823%2900267-9

One view of sarcoidosis is that the term covers many different diseases. However, no classification framework exists for the future exploration of pathogenetic pathways, genetic or trigger predilections, patterns of lung function impairment, or treat... Read More about High-resolution CT phenotypes in pulmonary sarcoidosis: a multinational Delphi consensus study.

Development of a Core Outcome Set for the research and assessment of malignant bowel obstruction (2023)
Journal Article
Bravington, A., Obita, G., Baddeley, E., Johnson, M., Murtagh, F., Currow, D., …Boland, J. (2023). Development of a Core Outcome Set for the research and assessment of malignant bowel obstruction. PLoS ONE, 18(8), Article e0289501. https://doi.org/10.1371/journal.pone.0289501

Background: Malignant bowel obstruction is experienced by 15% of people with advanced cancer, preventing them from eating and drinking and causing pain, nausea and vomiting. Surgery is not always appropriate. Management options include tube or stent... Read More about Development of a Core Outcome Set for the research and assessment of malignant bowel obstruction.

PCSK6 and Survival in Idiopathic Pulmonary Fibrosis (2023)
Journal Article
Oldham, J. M., Allen, R. J., Lorenzo-Salazar, J. M., Molyneaux, P. L., Ma, S. F., Joseph, C., …Noth, I. (2023). PCSK6 and Survival in Idiopathic Pulmonary Fibrosis. American Journal of Respiratory and Critical Care Medicine, 207(11), 1515-1524. https://doi.org/10.1164/rccm.202205-0845OC

Rationale: Idiopathic pulmonary fibrosis (IPF) is a devastating disease characterized by limited treatment options and high mortality. A better understanding of the molecular drivers of IPF progression is needed. Objectives: To identify and validate... Read More about PCSK6 and Survival in Idiopathic Pulmonary Fibrosis.