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All Outputs (358)

Magnetoencephalography to investigate central perception of exercise-induced breathlessness in people with chronic lung disease: A feasibility pilot (2015)
Journal Article
Johnson, M. J., Simpson, M. I., Currow, D. C., Millman, R. E., Hart, S. P., & Green, G. (2015). Magnetoencephalography to investigate central perception of exercise-induced breathlessness in people with chronic lung disease: A feasibility pilot. BMJ open, 5(6), Article ARTN e007535. https://doi.org/10.1136/bmjopen-2014-007535

Objectives: Neuroimaging in chronic breathlessness is challenging. The study objective was to test the feasibility of magnetoencephalography (MEG) for functional neuroimaging of people with chronic breathlessness. Design: Feasibility pilot study. Set... Read More about Magnetoencephalography to investigate central perception of exercise-induced breathlessness in people with chronic lung disease: A feasibility pilot.

Can variability in the effect of opioids on refractory breathlessness be explained by genetic factors? (2015)
Journal Article
Currow, D. C., Quinn, S., Ekström, M., Kaasa, S., Johnson, M. J., Somogyi, A. A., & Klepstad, P. (2015). Can variability in the effect of opioids on refractory breathlessness be explained by genetic factors?. BMJ open, 5(5), e006818-e006818. https://doi.org/10.1136/bmjopen-2014-006818

© 2015, BMJ Publishing Group. All rights reserved. Objectives: Opioids modulate the perception of breathlessness with a considerable variation in response, with poor correlation between the required opioid dose and symptom severity. The objective of... Read More about Can variability in the effect of opioids on refractory breathlessness be explained by genetic factors?.

A systematic review of strategies used to increase recruitment of people with cancer or organ failure into clinical trials: Implications for palliative care research (2015)
Journal Article
Boland, J., Currow, D. C., Wilcock, A., Tieman, J., Hussain, J. A., Pitsillides, C., Abernethy, A. P., & Johnson, M. J. (2015). A systematic review of strategies used to increase recruitment of people with cancer or organ failure into clinical trials: Implications for palliative care research. Journal of pain and symptom management, 49(4), 762-772. https://doi.org/10.1016/j.jpainsymman.2014.09.018

© 2015 American Academy of Hospice and Palliative Medicine. Context The challenges of palliative care clinical trial recruitment are well documented. Objectives The aim of the study was to review tested strategies to improve recruitment to trials of... Read More about A systematic review of strategies used to increase recruitment of people with cancer or organ failure into clinical trials: Implications for palliative care research.

Systematic review of compression following treatment for varicose veins (2015)
Journal Article
El-Sheikha, J., Carradice, D., Nandhra, S., Leung, C., Smith, G., Campbell, B., & Chetter, I. (2015). Systematic review of compression following treatment for varicose veins. British journal of surgery, 102(7), 719-725. https://doi.org/10.1002/bjs.9788

Background Consensus regarding compression following treatment of varicose veins has yet to be reached. This systematic review aims to establish the optimal compression regimen after venous treatment. Methods A systematic review of MEDLINE, Embase an... Read More about Systematic review of compression following treatment for varicose veins.

Risk factors for emergency presentation with lung and colorectal cancers: A systematic review (2015)
Journal Article
Mitchell, E. D., Pickwell-Smith, B., & Macleod, U. (2015). Risk factors for emergency presentation with lung and colorectal cancers: A systematic review. BMJ open, 5(4), Article e006965. https://doi.org/10.1136/bmjopen-2014-006965

© 2015, BMJ. All rights reserved. Objective: To identify patient and practitioner factors that influence cancer diagnosis via emergency presentation (EP). Design: Systematic review. Data sources: MEDLINE, EMBASE, CINAHL, EBM Reviews, Science and Soci... Read More about Risk factors for emergency presentation with lung and colorectal cancers: A systematic review.

A randomized clinical trial of endovenous laser ablation versus conventional surgery for small saphenous varicose veins (2015)
Journal Article
Nandhra, S., El-sheikha, J., Carradice, D., Wallace, T., Souroullas, P., Samuel, N., Smith, G., & Chetter, I. C. (2015). A randomized clinical trial of endovenous laser ablation versus conventional surgery for small saphenous varicose veins. Journal of vascular surgery, 61(3), 741-746. https://doi.org/10.1016/j.jvs.2014.09.037

Background: This randomized clinical trial compared endovenous laser ablation (EVLA) and surgical ligation with attempted stripping in the treatment of small saphenous vein (SSV) insufficiency. The early results demonstrated that EVLA was more likely... Read More about A randomized clinical trial of endovenous laser ablation versus conventional surgery for small saphenous varicose veins.

The role of primary care in cancer diagnosis via emergency presentation: qualitative synthesis of significant event reports (2015)
Journal Article
Mitchell, E. D., Rubin, G., Merriman, L., & Macleod, U. (2015). The role of primary care in cancer diagnosis via emergency presentation: qualitative synthesis of significant event reports. The British Journal of Cancer, 112(S1), S50-S56. https://doi.org/10.1038/bjc.2015.42

Background:
Patients diagnosed with cancer in the context of an emergency presentation (EP) have poorer outcomes. It is often assumed that such patients present to the emergency department without consulting their general practitioner (GP). Little w... Read More about The role of primary care in cancer diagnosis via emergency presentation: qualitative synthesis of significant event reports.

Is increased time to diagnosis and treatment in symptomatic cancer associated with poorer outcomes? Systematic review (2015)
Journal Article
Neal, R. D., Tharmanathan, P., France, B., Din, N. U., Cotton, S., Fallon-Ferguson, J., Hamilton, W., Hendry, A., Hendry, M., Lewis, R., Macleod, U., Mitchell, E. D., Pickett, M., Rai, T., Shaw, K., Stuart, N., Tørring, M. L., Wilkinson, C., Williams, B., Williams, N., & Emery, J. (2015). Is increased time to diagnosis and treatment in symptomatic cancer associated with poorer outcomes? Systematic review. The British Journal of Cancer, 112, S92-S107. https://doi.org/10.1038/bjc.2015.48

© 2015 Cancer Research UK. Background: It is unclear whether more timely cancer diagnosis brings favourable outcomes, with much of the previous evidence, in some cancers, being equivocal. We set out to determine whether there is an association betwee... Read More about Is increased time to diagnosis and treatment in symptomatic cancer associated with poorer outcomes? Systematic review.

Compression regimes after endovenous ablation for superficial venous insufficiency – A survey of members of the Vascular Society of Great Britain and Ireland (2015)
Journal Article
El-Sheikha, J., Nandhra, S., Carradice, D., Acey, C., Smith, G., Campbell, B., & Chetter, I. (2016). Compression regimes after endovenous ablation for superficial venous insufficiency – A survey of members of the Vascular Society of Great Britain and Ireland. Phlebology, 31(1), 16-22. https://doi.org/10.1177/0268355514567732

Introduction: The optimal compression regime following ultrasound guided foam sclerotherapy (UGFS), radiofrequency ablation (RFA) and endovenous laser ablation (EVLA) for varicose veins is not known. The aim of this study was to document current prac... Read More about Compression regimes after endovenous ablation for superficial venous insufficiency – A survey of members of the Vascular Society of Great Britain and Ireland.

The value of telehealth in the early detection of chronic obstructive pulmonary disease exacerbations: A prospective observational study (2015)
Journal Article
Hamad, G. A., Crooks, M., & Morice, A. H. (2016). The value of telehealth in the early detection of chronic obstructive pulmonary disease exacerbations: A prospective observational study. Health Informatics Journal, 22(2), 406-413. https://doi.org/10.1177/1460458214564434

© 2014 The Author(s). We aim to establish the value of telemonitoring in the early detection of chronic obstructive pulmonary disease exacerbations. We followed up patients undergoing chronic obstructive pulmonary disease telemonitoring for 4 months.... Read More about The value of telehealth in the early detection of chronic obstructive pulmonary disease exacerbations: A prospective observational study.

Measuring patient-perceived continuity of care for patients with long-term conditions in primary care (2014)
Journal Article
Hill, K. M., Twiddy, M., Hewison, J., & House, A. O. (2014). Measuring patient-perceived continuity of care for patients with long-term conditions in primary care. BMC family practice, 15(1), Article 191. https://doi.org/10.1186/s12875-014-0191-8

Background: Continuity of care is widely acknowledged as important for patients with multi-morbidity but simple,
service-orientated indices cannot capture the full impact of continuity in complex care delivery systems. The patient’s
perspective is im... Read More about Measuring patient-perceived continuity of care for patients with long-term conditions in primary care.

Variability in clinicians' opinions regarding fitness to drive in patients with obstructive sleep apnoea syndrome (OSAS) (2014)
Journal Article
Dwarakanath, A., Twiddy, M., Ghosh, D., Jamson, S. L., Baxter, P. D., & Elliott, M. W. (2015). Variability in clinicians' opinions regarding fitness to drive in patients with obstructive sleep apnoea syndrome (OSAS). Thorax, 70(5), 495-497. https://doi.org/10.1136/thoraxjnl-2014-206180

We evaluated clinicians' current practice for giving advice to patients with obstructive sleep apnoea syndrome. Clinicians were invited to complete a web-based survey and indicate the advice they would give to patients in a number of scenarios about... Read More about Variability in clinicians' opinions regarding fitness to drive in patients with obstructive sleep apnoea syndrome (OSAS).

Double-blind, placebo-controlled, randomized trial of octreotide in malignant bowel obstruction (2014)
Journal Article
Currow, D. C., Quinn, S., Agar, M., Fazekas, B., Hardy, J., McCaffrey, N., Eckermann, S., Abernethy, A. P., & Clark, K. (2015). Double-blind, placebo-controlled, randomized trial of octreotide in malignant bowel obstruction. Journal of pain and symptom management, 49(5), 814-821. https://doi.org/10.1016/j.jpainsymman.2014.09.013

Context Does octreotide reduce vomiting in cancer-associated bowel obstruction? Objectives To evaluate the net effect of adding octreotide or placebo to standardized therapies on the number of days free of vomiting for populations presenting with vom... Read More about Double-blind, placebo-controlled, randomized trial of octreotide in malignant bowel obstruction.

A comparison of the effectiveness of treating those with and without the complications of superficial venous insufficiency (2014)
Journal Article
Carradice, D., Wallace, T., Gohil, R., & Chetter, I. (2014). A comparison of the effectiveness of treating those with and without the complications of superficial venous insufficiency. Annals of Surgery, 260(2), 396-401. https://doi.org/10.1097/sla.0000000000000541

Objective: To test the hypothesis that patients with soft tissue changes related to superficial venous insufficiency (SVI) have greater benefits from treatment than those with only symptomatic varicose veins.
Background: A commonly held view is that... Read More about A comparison of the effectiveness of treating those with and without the complications of superficial venous insufficiency.

Understanding causal associations between self-rated health and personal relationships in older adults: a review of evidence from longitudinal studies (2014)
Journal Article
Craigs, C. L., Twiddy, M., Parker, S. G., & West, R. M. (2014). Understanding causal associations between self-rated health and personal relationships in older adults: a review of evidence from longitudinal studies. Archives of Gerontology and Geriatrics, 59(2), 211-226. https://doi.org/10.1016/j.archger.2014.06.009

Abstract
Background

As we age we experience many life changes in our health, personal relationships, work, or home life which can impact on other aspects of our life. There is compelling evidence that how we feel about our health influences, or is i... Read More about Understanding causal associations between self-rated health and personal relationships in older adults: a review of evidence from longitudinal studies.

The rural bite in population pyramids: what are the implications for responsiveness of health systems in middle income countries? (2014)
Journal Article
Jahan, N. K., Allotey, P., Arunachalam, D., Yasin, S., Soyiri, I. N., Davey, T. M., & Reidpath, D. D. (2014). The rural bite in population pyramids: what are the implications for responsiveness of health systems in middle income countries?. BMC public health, 14(Suppl 2), S8. https://doi.org/10.1186/1471-2458-14-S2-S8

Background
Health services can only be responsive if they are designed to service the needs of the population at hand. In many low and middle income countries, the rate of urbanisation can leave the profile of the rural population quite different fro... Read More about The rural bite in population pyramids: what are the implications for responsiveness of health systems in middle income countries?.

Clinical outcomes and quality of life 5 years after a randomized trial of concomitant or sequential phlebectomy following endovenous laser ablation for varicose veins (2014)
Journal Article
El-Sheikha, J., Nandhra, S., Carradice, D., Wallace, T., Samuel, N., Smith, G., & Chetter, I. C. (2014). Clinical outcomes and quality of life 5 years after a randomized trial of concomitant or sequential phlebectomy following endovenous laser ablation for varicose veins. British journal of surgery, 101(9), 1093-1097. https://doi.org/10.1002/bjs.9565

BackgroundEndovenous laser ablation (EVLA) is a popular treatment for superficial venous insufficiency. Debate continues regarding the optimal management of symptomatic varicose tributaries following ablation of the main saphenous trunk. This randomi... Read More about Clinical outcomes and quality of life 5 years after a randomized trial of concomitant or sequential phlebectomy following endovenous laser ablation for varicose veins.

Cohorts and community: A case study of community engagement in the establishment of a health and demographic surveillance site in Malaysia (2014)
Journal Article
Allotey, P., Reidpath, D. D., Devarajan, N., Rajagobal, K., Yasin, S., Arunachalam, D., Imelda, J. D., Soyiri, I., Davey, T., Jahan, N., & The Seaco Team. (2014). Cohorts and community: A case study of community engagement in the establishment of a health and demographic surveillance site in Malaysia. Global Health Action, 7(1), 23176. https://doi.org/10.3402/gha.v7.23176

Background: Community engagement is an increasingly important requirement of public health research and plays an important role in the informed consent and recruitment process. However, there is very little guidance about how it should be done, the i... Read More about Cohorts and community: A case study of community engagement in the establishment of a health and demographic surveillance site in Malaysia.

Randomized clinical trial of selective versus routine preoperative duplex ultrasound imaging before arteriovenous fistula surgery: Duplex imaging before arteriovenous fistula surgery (2014)
Journal Article
Barnes, R., Chetter, I. C., & Smith, G. E. (2014). Randomized clinical trial of selective versus routine preoperative duplex ultrasound imaging before arteriovenous fistula surgery: Duplex imaging before arteriovenous fistula surgery. British journal of surgery, 101(5), 469-474. https://doi.org/10.1002/bjs.9435

BackgroundAnatomical suitability for arteriovenous fistula (AVF) formation was formerly determined by clinical examination alone. There are potential benefits from imaging to assess anatomical suitability. Existing studies examined the role of routin... Read More about Randomized clinical trial of selective versus routine preoperative duplex ultrasound imaging before arteriovenous fistula surgery: Duplex imaging before arteriovenous fistula surgery.