Blood pressure lowering and prevention of dementia: an individual patient data meta-analysis

Peters, Ruth; Xu, Ying; Fitzgerald, Oisin; Aung, Htein Linn; Beckett, Nigel; Bulpitt, Christopher; Chalmers, John; Forette, Francoise; Gong, Jessica; Harris, Katie; Humburg, Peter; Matthews, Fiona E.; Staessen, Jan A.; Thijs, Lutgarde; Tzourio, Christophe; Warwick, Jane; Woodward, Mark; Anderson, Craig S.

doi:10.1093/eurheartj/ehac584

All Outputs (3)

Conclusions (2022)
Book Chapter
Williams, T. M. (2022). Conclusions. In T. M. Williams, K. Samset, & G. Holst Volden (Eds.), The Front-end of Large Public Projects: Paradoxes and Ways Ahead (191-204). Taylor & Francis (Routledge). https://doi.org/10.4324/9781003257172-8

Projects are the key organisational form used to deliver transformational policy change and build new systems in the public sector. Traditional thinking has looked at the project as an exercise to carry out a defined task in a specific time, at a spe... Read More about Conclusions.

Project success (2022)
Book Chapter
Williams, T. M. (2022). Project success. In T. M. Williams, K. Samset, & G. Holst Volden (Eds.), The Front-end of Large Public Projects: Paradoxes and Ways Ahead (10-42). London: Taylor & Francis (Routledge). https://doi.org/10.4324/9781003257172-2

This chapter looks at the academic background to this question, dividing the idea of success into strategic and tactical success. It looks at the various paradoxes that accompany major public projects as criteria for success are developed. The combin... Read More about Project success.

Blood pressure lowering and prevention of dementia: an individual patient data meta-analysis (2022)
Journal Article
Peters, R., Xu, Y., Fitzgerald, O., Aung, H. L., Beckett, N., Bulpitt, C., Chalmers, J., Forette, F., Gong, J., Harris, K., Humburg, P., Matthews, F. E., Staessen, J. A., Thijs, L., Tzourio, C., Warwick, J., Woodward, M., & Anderson, C. S. (2022). Blood pressure lowering and prevention of dementia: an individual patient data meta-analysis. European Heart Journal, 43(48), 4980-4990. https://doi.org/10.1093/eurheartj/ehac584

Aims Observational studies indicate U-shaped associations of blood pressure (BP) and incident dementia in older age, but randomized controlled trials of BP-lowering treatment show mixed results on this outcome in hypertensive patients. A pooled indiv... Read More about Blood pressure lowering and prevention of dementia: an individual patient data meta-analysis.